Influenza-A Circulation in Vietnam through Data Analysis of Hemagglutinin Entires

Author

Ly Le ; Hong-Quang Nguyen

Author_Institution

Sch. of Biotechnol., Int. Univ., Ho Chi Minh City, Vietnam

fYear

2013

fDate

24-27 June 2013

Firstpage

204

Lastpage

206

Abstract

Hemagglutinin is a glycoprotein locating on surface of influenza virus. Influenza A human hemagglutinin protein H1, H2, H3, H5, H7, H9 sequences on NCBI database from Vietnam were retrieved and analyzed to find out the pattern of viral circulation within the country in the last 12 years. 1060 sequences were collected and analyzed. The results revealed five main influenza A virus including H5N1, H3N2, H1N1, H6N2, and H9N2 circulating in Vietnam with high level of genetic compatibility, identified as reassortants between a wide variety viral genotypes and share common mechanisms of spread. The most two popular host are human and poultry. The two recent pandemics avian H5N1 in 2005 and Swine H1N1 in 2009 did show significant effects on the viral circulation in Vietnam. H5N1 and H1N1 subtype remain pathogenic and require close surveillance.

Keywords

biology computing; data analysis; diseases; epidemics; H1 sequences; H2 sequences; H3 sequences; H3N2; H5 sequences; H6N2; H7 sequences; H9 sequences; H9N2; NCBI database; Vietnam; avian H5N1; data analysis; glycoprotein; hemagglutinin entires; influenza A human hemagglutinin protein; influenza virus; influenza-A circulation; pandemics; poultry; swine H1N1; viral genotypes; Educational institutions; Genetics; Influenza; Proteins; RNA; Strain; Hemagglutinin Entires; Influenza-A Circulation; Viral circulation;

fLanguage

English

Publisher

ieee

Conference_Titel

Computational Science and Its Applications (ICCSA), 2013 13th International Conference on

Conference_Location

Ho Chi Minh City

Type

conf

DOI

10.1109/ICCSA.2013.42

Filename

6681125