Title :
Simulating lesions in multi-layer, multi-columnar model of neocortex
Author :
Strack, Beata ; Jacobs, Kimberle M. ; Cios, Krzysztof J.
Author_Institution :
Sch. of Eng., Dept. of Comput. Sci., Virginia Commonwealth Univ., Richmond, VA, USA
Abstract :
The paper presents results of modeling global and focal loss of layers in a multi-columnar model of neocortex. Specifically, the spread of activity across columns in conditions of inhibitory blockade is compared. With very low inhibition activity spreads through all layers, however, deep layers are critical for spread of activity when inhibition is only moderately blocked.
Keywords :
bioelectric potentials; brain; neurophysiology; physiological models; lesion simulation; neocortex inhibition activity; neocortex inhibitory blockade; neocortex multicolumnar model; neocortex multilayer model; Biological system modeling; Brain modeling; Bridges; Computational modeling; Educational institutions; Neurons; Strips;
Conference_Titel :
Neural Engineering (NER), 2013 6th International IEEE/EMBS Conference on
Conference_Location :
San Diego, CA
DOI :
10.1109/NER.2013.6696064
