• DocumentCode
    667359
  • Title

    Computational study of particle deposition in patient specific geometries

  • Author

    Pilou, Marika ; Skiadopoulos, Anastasios ; Makris, Evangelos ; Neofytou, Panagiotis ; Housiadas, Christos

  • Author_Institution
    Thermal Hydraulics & Multiphase Flow Lab., INRASTES, Agia Paraskevi, Greece
  • fYear
    2013
  • fDate
    10-13 Nov. 2013
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    The present work focuses on the study of particle deposition in segments of the cardiovascular system. In particular, the geometry of an iliac bifurcation is reconstructed from medical imaging data and the flow fields of both blood and particles are obtained using Computational Fluid Particle Dynamics techniques. Particle convection, diffusion and inertia are taken into account in the simulations. The numerical experiments indicate that diffusion dominates deposition and only 10% of the injected particles deposit in the bifurcation. Both blood flow field and the characteristics of the patient specific geometry influence the particle deposition sites. Overall, the proposed methodology could become a useful tool for the design and optimization of biomedical applications.
  • Keywords
    bifurcation; biological fluid dynamics; cardiovascular system; computational fluid dynamics; image reconstruction; medical image processing; biomedical applications; blood flow fields; cardiovascular system; computational fluid particle dynamics techniques; iliac bifurcation; medical imaging data; optimization; particle convection; particle deposition sites; particle flow fields; patient specific geometries; Bifurcation; Biomedical imaging; Fluid flow; Fluids; Geometry; Mathematical model;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Bioengineering (BIBE), 2013 IEEE 13th International Conference on
  • Conference_Location
    Chania
  • Type

    conf

  • DOI
    10.1109/BIBE.2013.6701697
  • Filename
    6701697