Isolation of Circulating Tumor Cells by convective self-assembly technique

The CTCs (Circulating Tumor Cells) isolation method enables to sort very rare single CTC from the whole blood. We utilized the technique of convective self-assembly, which is a technique for depositing cells onto the microfluidic channel, to isolate CTCs. Through the convective self-assembly processes, the cells including CTCs and blood cells are deposited in the channels of microfluidic chip. After giving the sheath flow, only the CTCs remain in the channels and the other cells are removed. As the result, it was indicated that a specific design of microchannel has the highest collection rate of about 90%.