Realistic 3D bidomain model of whole heart electrical activity and ECG generation

Author

Sovilj, Sinisa ; Magjarevic, Ratko ; Lovell, Nigel ; Dokos, Socrates

Author_Institution

Fac. of Electr. Eng. & Comput., Univ. of Zagreb, Zagreb, Croatia

fYear

2013

fDate

22-25 Sept. 2013

Firstpage

377

Lastpage

380

Abstract

This study describes an anatomically realistic 3D bidomain model of whole-heart electrical activity. The heart was embedded in a human torso, incorporating spontaneous activation of the sinoatrial node and including conduction through the specialized conduction pathways with heterogeneous action potential (AP) morphologies throughout the heart. The model was able to generate realistic ECG waveforms, and is proposed as a useful tool for investigating the effects of altered myocardial electrical properties on the ECG.

Keywords

bioelectric potentials; biological tissues; computerised tomography; electrocardiography; image segmentation; medical image processing; physiological models; ECG generation; ECG waveforms; altered myocardial electrical properties; anatomic realistic 3D bidomain model; heterogeneous action potential morphologies; human torso; sinoatrial node; specialized conduction pathways; whole-heart electrical activity; Biological system modeling; Computational modeling; Conductivity; Electrocardiography; Heart; Mathematical model; Torso;

fLanguage

English

Publisher

ieee

Conference_Titel

Computing in Cardiology Conference (CinC), 2013

Conference_Location

Zaragoza

ISSN

2325-8861

Print_ISBN

978-1-4799-0884-4

Type

conf

Filename

6713392