DocumentCode :
674581
Title :
Extracting myofibre orientation from micro-CT images: An optimisation study
Author :
Haibo Ni ; Castro, Simon J. ; Stephenson, Robert S. ; Jarvis, Jonathan C. ; Lowe, Tristan ; Hart, George ; Boyett, M.R. ; Henggui Zhang
Author_Institution :
Biol. Phys. Group, Univ. of Manchester, Manchester, UK
fYear :
2013
fDate :
22-25 Sept. 2013
Firstpage :
823
Lastpage :
826
Abstract :
Recent studies introduced intensity based structure tensor analysis to extract the myocardium structure from micro X-ray computed tomography (micro-CT) images. The implementation of this method is empirical and encounters difficulties in validating the results. In this study, we performed series of tests using structure tensor analysis on synthetic tissue wedges with predefined fibre orientations, optimised the parameters of the method and applied it to the micro-CT images of a rabbit ventricular tissue. The accuracy of the method with several derivative filters and various parameters was investigated by quantifying the error in estimation in inclination angles. A measure of coherence was implemented to assess the coherence and reliability of the extracted orientations. We introduced Gaussian noise to investigate the robustness of this method. Our results suggest that the derivative of Gaussian and optimised Sobel derivative filter have better and balanced performances with overall mean error around 4°. The scale parameters play an important role in securing the accuracy. The algorithm is resistant to Gaussian noise. Using this method the myofibre orientation was successfully extracted from the ventricular tissue wedge images of the rabbit heart.
Keywords :
Gaussian noise; biological tissues; cardiology; computerised tomography; diagnostic radiography; feature extraction; mean square error methods; medical image processing; optimisation; tensors; Gaussian noise; coherence measurement; inclination angle estimation; intensity based structure tensor analysis; mean error; microX-ray computed tomography images; myocardium structure extraction; myofibre orientation extraction; optimized Sobel derivative filter; rabbit heart; rabbit ventricular tissue wedge images; Abstracts; Biology; Computed tomography; Robustness; Structural engineering; Tensile stress;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computing in Cardiology Conference (CinC), 2013
Conference_Location :
Zaragoza
ISSN :
2325-8861
Print_ISBN :
978-1-4799-0884-4
Type :
conf
Filename :
6713504
Link To Document :
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