• DocumentCode
    677950
  • Title

    Online Process Identification of Hypnosis

  • Author

    Wolf, Helmut ; Sievert, A. ; Drewelow, Wolfgang ; Jeinsch, Torsten ; Janda, Marcel ; Bajorat, J. ; Simanski, O.

  • Author_Institution
    Control Applic. Center, Univ. of Rostock, Rostock, Germany
  • fYear
    2013
  • fDate
    13-16 Oct. 2013
  • Firstpage
    2225
  • Lastpage
    2230
  • Abstract
    For most kinds of surgeries an adequate anaesthesia is necessary. Three main components characterise an anaesthesia - the relaxation, the analgesia and the hypnosis. This paper treats the topic of the Propofol/ Remifentanil induced hypnosis. We try to find a suitable model structure for the online identification of this process during a surgery. After a review of known models from literature an own model approach was developed and validated. By an offline optimisation study the parameter estimation problem of the defined cost function was examined. An online approach based on a recursive, iterative gradient algorithm was implemented. The quality of the identified parameters could be verified using measurements of surgeries.
  • Keywords
    drugs; gradient methods; parameter estimation; surgery; anaesthesia; analgesia; defined cost function; iterative gradient algorithm; offline optimisation; online identification; online process identification; parameter estimation problem; propofol induced hypnosis; recursive gradient algorithm; remifentanil induced hypnosis; surgeries; Anesthesia; Brain modeling; Cost function; Drugs; Mathematical model; Surgery; BIS; Depth of Anesthesia; Online Identification; PKPD; Propofol; Remifentanil;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Systems, Man, and Cybernetics (SMC), 2013 IEEE International Conference on
  • Conference_Location
    Manchester
  • Type

    conf

  • DOI
    10.1109/SMC.2013.381
  • Filename
    6722134