• DocumentCode
    705490
  • Title

    Biosensor and breast cancer treatment

  • Author

    Sivasankaran, Nivetha

  • Author_Institution
    St.Joseph´s Coll. Of Eng., Chennai, India
  • fYear
    2015
  • fDate
    18-20 Feb. 2015
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    Biosensor based technique for breast cancer treatment uses an encapsulation technique in which biosensor cages radioactive bacteria (Listeria) that are encapsulated within a polymeric membrane (Polycaprolactone). This method is used to deliver targeted therapy to the cancer cell. Biosensor is designed to accommodate antibodies specific to cancer cell´s surface marker. When the biosensor comes across these surface markers, complementary binding between antibody and surface marker takes place that leads to the generation of mechanical energy by biosensor. This energy is transmitted to the underlying polymer, so that it ruptures the polymeric membrane, consequently, the radioactive bacteria is released to the site of action, thereby destroying the cancerous cell. This technique prevents the damage of nearby healthy cells that happens in the conventional chemotherapy or radiation therapy.
  • Keywords
    biosensors; cancer; cellular biophysics; encapsulation; membranes; microorganisms; molecular biophysics; polymers; proteins; radiation therapy; tumours; Listeria; antibodies; biosensor; breast cancer treatment; cancer cell; cancer cell surface marker; cancerous cell; complementary binding; conventional chemotherapy; encapsulation technique; healthy cells; mechanical energy; polycaprolactone; polymeric membrane; radiation therapy; radioactive bacteria; targeted therapy delivery; Biochemistry; Biosensors; Breast cancer; Microorganisms; Polymers; Surface treatment; antibody; biosensor; breast cancer; polymeric membrane (polycaprolactone); radioactive bacteria (Listeria); surface marker;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Robotics, Automation, Control and Embedded Systems (RACE), 2015 International Conference on
  • Conference_Location
    Chennai
  • Type

    conf

  • DOI
    10.1109/RACE.2015.7097239
  • Filename
    7097239