• DocumentCode
    710049
  • Title

    Computational study of secondary structure of premature miRNA and inclusion of finite state automation

  • Author

    Nath, Joyshree ; Nath, Asoke

  • Author_Institution
    Indian Stat. Inst., Kolkata, India
  • fYear
    2013
  • fDate
    15-18 Dec. 2013
  • Firstpage
    291
  • Lastpage
    298
  • Abstract
    For the past few years quite a lot of research has been done on pre-mature and mature miRNAs. Scientists show huge interest in this domain, as this domain is still not explored fully. It is believed to have better information on animal and plant structures and functions. Quite an amount of work has been done in assessing miRNA functions, mapping their expressions with genetic disorders, discovering correct miRNA targets and lots more. So in experimental or computational genomics perfect assessing of the structural and functional behavior of miRNAs correctly is a huge task. In this paper the authors have made a systematic study to get a proper secondary structure of the pre-mature miRNA and get the mature miRNA sequence corresponding to it. The similarities of the computational results with the experimental results will pave a new way towards certifying novel miRNAs using computational method. In the present paper the authors have introduced finite state automation to represent the secondary structure. The finite state automation approach will give better understanding the structural and functional behavior of miRNA.
  • Keywords
    RNA; biology computing; finite state machines; computational genomics; experimental genomics; finite state automation; genetic disorders; premature miRNA; secondary structure; Gold; chemicals on miRNAs; computational secondary structure; finite state automata; mature miRNA; premature miRNA; structural behavior;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Information and Communication Technologies (WICT), 2013 Third World Congress on
  • Conference_Location
    Hanoi
  • Type

    conf

  • DOI
    10.1109/WICT.2013.7113151
  • Filename
    7113151