Title :
Ga-containing bioactive glass/Dextran-CMC hydrogel composites: Ion release and cell viability
Author :
Keenan, T.J. ; Hall, M.M. ; Wren, A.W.
Author_Institution :
Kazuo Inamori Sch. of Eng., Alfred Univ., Alfred, NY, USA
Abstract :
This study aims to investigate the solubility of composites comprised of a degradable polymeric hydrogel and particles of a Ga-containing glass series, and relate this solubility information to the viability of MC-3T3 osteoblasts. Composites released a maximum of 4.7 mg/L of Ga after 30 days, and these extracts did not inhibit osteoblast viability.
Keywords :
biodegradable materials; biomedical materials; cellular biophysics; filled polymers; gallium; glass; hydrogels; ion exchange; solubility; Ga-containing bioactive glass-dextran-CMC hydrogel composites; Ga-containing glass series; MC-3T3 osteoblasts viability; SiO2:Ga; cell viability; degradable polymeric hydrogel; ion release; solubility information; time 30 d; Bones; Gallium; Glass; Loading; Polymers; Scanning electron microscopy; Spectroscopy;
Conference_Titel :
Biomedical Engineering Conference (NEBEC), 2015 41st Annual Northeast
Conference_Location :
Troy, NY
Print_ISBN :
978-1-4799-8358-2
DOI :
10.1109/NEBEC.2015.7117171
