A scalable high performance client/server framework to manage and analyze high dimensional datasets recorded by 4096 CMOS-MEAs

Large scale CMOS-MEAs are an emerging neurotechnology enabling extracellular recordings in-vitro and in-vivo with thousand´s electrodes simultaneously. This is on the way to provide the unprecedented capability of acquiring signals from several thousands of single-units, thus opening novel perspectives for electrophysiology, but also novel challenges for analysis and management of large datasets. Here, we propose an analysis platform designed for managing unprecedentedly large datasets of electrical recordings acquired with a 4096-electrode array platform. Furthermore it provides a computational framework to facilitate the development and integration of new analysis tools exploiting high-resolution electrical recordings.