• DocumentCode
    72680
  • Title

    Capsule-Type Magnetic Microrobot Actuated by an External Magnetic Field for Selective Drug Delivery in Human Blood Vessels

  • Author

    Kyun Choi ; Gunhee Jang ; Seungmun Jeon ; Jaekwang Nam

  • Author_Institution
    Dept. of Mech. Eng., Hanyang Univ., Seoul, South Korea
  • Volume
    50
  • Issue
    11
  • fYear
    2014
  • fDate
    Nov. 2014
  • Firstpage
    1
  • Lastpage
    4
  • Abstract
    In this paper, we propose a novel capsule-type magnetic microrobot (CMM) that can navigate along a tubular environment and selectively release drugs in different target points actuated by a magnetic navigation system. The proposed CMM is a capsule-type structure with two cylindrical drug chambers that contain different drugs. It can navigate through a tubular environment by a magnetic gradient and release drugs at different positions by using uniform rotating magnetic fields. The proposed CMM was prototyped using 3-D printing technology. The operating conditions of a drug-releasing motion were determined by investigating the magnetic and friction torques within the body. Finally, we performed various experiments in a tubular environment to verify the validity of the proposed CMM.
  • Keywords
    bioMEMS; biomagnetism; blood vessels; drug delivery systems; drugs; friction; magnetic actuators; magnetic variables control; medical robotics; microrobots; motion control; three-dimensional printing; torque; torque control; 3D printing technology; capsule-type magnetic microrobot actuation; capsule-type structure; cylindrical drug chambers; drug-releasing motion; external magnetic field; friction torques; human blood vessels; magnetic navigation system; magnetic torques; selective drug delivery; tubular environment; uniform rotating magnetic fields; Coordinate measuring machines; Drugs; Fasteners; Magnetic flux; Navigation; Permanent magnets; Torque; Magnetic microrobot; magnetic navigation system; rotating screw motion; targeted drug delivery;
  • fLanguage
    English
  • Journal_Title
    Magnetics, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9464
  • Type

    jour

  • DOI
    10.1109/TMAG.2014.2325055
  • Filename
    6971729