High-resolution neural depth probe with integrated 460 NM light emitting diode for optogenetic applications

Author

Schwaerzle, M. ; Pothof, F. ; Paul, O. ; Ruther, P.

Author_Institution

Dept. of Microsyst. Eng. (IMTEK), Univ. of Freiburg, Freiburg, Germany

fYear

2015

fDate

21-25 June 2015

Firstpage

1774

Lastpage

1777

Abstract

We report on the design, assembly, and optical as well as thermal characterization of a polymer-based optrode with an integrated light source for applications in optogenetics. The novel probe allows to optically stimulate neural brain tissue in deeper brain regions and to simultaneously record brain activity using integrated macroelectrodes and microelectrodes. The optrode is based on a cylindrical polyimide (PI) probe carrying the electrodes and their respective wiring. A bare light emitting diode (LED) chip is integrated within this cylinder and electrically interconnected through a separate PI-based ribbon cable.

Keywords

biological tissues; biomedical electrodes; brain; genetics; light emitting diodes; microelectrodes; neurophysiology; patient treatment; LED chip; cylindrical polyimide probe; high-resolution neural depth probe; integrated light source; light emitting diode; macroelectrodes; microelectrodes; neural brain tissue; optogenetic applications; polymer-based optrode; wavelength 460 nm; Biomedical optical imaging; Integrated optics; Light emitting diodes; Optical device fabrication; Optical fibers; Probes; Stimulated emission; Neural depth probe; deep brain stimulation; integrated light source; light emitting diode; optogenetic;

fLanguage

English

Publisher

ieee

Conference_Titel

Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), 2015 Transducers - 2015 18th International Conference on

Conference_Location

Anchorage, AK

Type

conf

DOI

10.1109/TRANSDUCERS.2015.7181290

Filename

7181290