• DocumentCode
    732467
  • Title

    Visualizing mammalian brain area interactions by dual-axis two-photon calcium imaging

  • Author

    Schnitzer, Mark

  • Author_Institution
    Depts. of Biol. & Appl. Phys., Stanford Univ., Stanford, CA, USA
  • fYear
    2015
  • fDate
    10-15 May 2015
  • Firstpage
    1
  • Lastpage
    1
  • Abstract
    Fluorescence Ca2+ imaging enables large-scale recordings of neural activity, but collective dynamics across mammalian brain regions are generally inaccessible within single fields of view. Here we introduce a two-photon microscope possessing two articulated arms that can simultaneously image two brain areas (~0.38 mm2 each), either nearby or distal, using microendoscopes, in awake behaving rodents.
  • Keywords
    biomedical optical imaging; brain; calcium; endoscopes; fluorescence; neurophysiology; optical microscopy; two-photon processes; articulated arms; awake behaving rodents; collective dynamics; dual-axis two-photon calcium imaging; fluorescence Ca2+ imaging; large-scale recordings; mammalian brain area interaction visualization; microendoscopes; neural activity; two-photon microscope; Biomedical imaging; Biotechnology; Brain; Microscopy; Optical microscopy;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics (CLEO), 2015 Conference on
  • Conference_Location
    San Jose, CA
  • Type

    conf

  • Filename
    7182899