• DocumentCode
    733666
  • Title

    An azimuthal polarizer assures localization accuracy in single-molecule super-resolution fluorescence microscopy

  • Author

    Lew, Matthew D. ; Moerner, W.E.

  • Author_Institution
    Depts. of Chem., Stanford Univ., Stanford, CA, USA
  • fYear
    2015
  • fDate
    10-15 May 2015
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    Imaging only azimuthally-polarized light from single fluorescent molecules avoids emission from the z component of their transition dipole moments, resulting in accurate measurement of location regardless of emitter orientation and degree of objective lens misfocus.
  • Keywords
    biomedical optical imaging; fluorescence; lenses; molecular biophysics; molecular moments; optical microscopy; optical polarisers; azimuthal polarizer; emitter orientation; localization accuracy; objective lens misfocus; single-molecule super-resolution fluorescence microscopy; transition dipole moments; Accuracy; Fluorescence; Image resolution; Lenses; Microscopy; Optical microscopy;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics (CLEO), 2015 Conference on
  • Conference_Location
    San Jose, CA
  • Type

    conf

  • Filename
    7184107