Molecular Imaging of Cancer: Applications of Magnetic Resonance Methods

Author

Gimi, Barjor ; Pathak, Arvind P. ; Ackerstaff, Ellen ; Glunde, Kristine ; Artemov, Dmitri ; Bhujwalla, Zaver M.

Author_Institution

Cellular Molecular Imaging Center, Johns Hopkins Univ., Baltimore, MD, USA

Volume

93

Issue

4

fYear

2005

fDate

4/1/2005 12:00:00 AM

Firstpage

784

Lastpage

799

Abstract

Cancer is a complex disease exhibiting a host of phenotypic diversities. Noninvasive multinuclear magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI) provide an array of capabilities to characterize and understand several of the vascular, metabolic, and physiological characteristics unique to cancer. The availability of targeted contrast agents has widened the scope of MR techniques to include the detection of receptor and gene expression. In this paper, we have highlighted the application of several MR techniques in imaging and understanding cancer.

Keywords

biomedical MRI; cancer; molecular biophysics; cancer; contrast agents; gene expression; magnetic resonance spectroscopic imaging; molecular imaging; noninvasive multinuclear magnetic resonance imaging; phenotypic diversities; receptor expression; vascular imaging; Cancer; Content addressable storage; Diseases; Gene expression; Magnetic resonance; Magnetic resonance imaging; Molecular imaging; Probes; Protons; Spectroscopy; Cancer; magnetic resonance imaging (MRI); magnetic resonance spectroscopic imaging (MRSI); metabolism; molecular imaging; receptor expression; vascular imaging;

fLanguage

English

Journal_Title

Proceedings of the IEEE

Publisher

ieee

ISSN

0018-9219

Type

jour

DOI

10.1109/JPROC.2005.844266

Filename

1412105