• DocumentCode
    755887
  • Title

    Building innovative representations of DNA sequence facilitate gene finding

  • Author

    Gao, Jianbo ; Cao, Yinhe ; Qi, Yan ; Hu, Jing

  • Author_Institution
    Dept. of Electr. & Comput. Eng., Florida Univ., Gainesville, FL, USA
  • Volume
    20
  • Issue
    6
  • fYear
    2005
  • Firstpage
    34
  • Lastpage
    39
  • Abstract
    Indices that can discriminate DNA sequences´ coding and noncoding regions are crucial elements of a successful gene identification algorithm. Multiscale analysis of various species´ genome sequences facilitates construction of novel codon indices. We´ve developed two novel DNA codon indices, one based on recurrence time and one based on fractal deviation. Because both work well on short DNA sequences, they both hold the promise of being integrated into and thus improving existing gene identification algorithms.
  • Keywords
    DNA; biology computing; genetics; sequences; DNA codon indices; DNA sequence; gene identification algorithm; genome sequences; Amino acids; Bioinformatics; DNA; Entropy; Fourier transforms; Genomics; Hidden Markov models; Information resources; Proteins; Sequences; entropy; fractal scaling breakdown; gene identification; period-3; recurrence time;
  • fLanguage
    English
  • Journal_Title
    Intelligent Systems, IEEE
  • Publisher
    ieee
  • ISSN
    1541-1672
  • Type

    jour

  • DOI
    10.1109/MIS.2005.100
  • Filename
    1556513