Fundamental considerations for biomaterial selection

The human body is the result of millions of years of evolution during which countless variations and trials driven by a commanding environment occurred. The result is a magnificent display of efficiency, robustness, and complexity. Trying to introduce incredibly simple instruments into such a complex structure is challenging. Because of the complex nature of the human body, specific problems with biomaterial biocompatibility and function are almost impossible to predict without extensive testing in cell cultures as well as in living systems. Because of the extensive nature of these tests, strict regulatory protocols are required to ensure that reliable products are produced. The considerations for the selection of biomaterials presented in this article are fundamental. Before proceeding to the advanced stages of instrument design and implementation, it is imperative that a biomaterial prove itself in regard to these primary issues. As the field of biomechanical engineering progresses and new biomaterials are needed for exciting new designs, these fundamental considerations for biomaterials selection may change. However, the basic principals guiding them will remain paramount to any person wishing to design a functional instrument