Effects of Magnetic Field and Magnetoliposomes on Mice: Cytotoxicity and Genotoxicity Tests

Author

Barbosa, Luzirlane S. ; Sadeghiani, Neda ; Guedes, Maria H A ; Oliveira, Daniela M. ; Tedesco, Antonio C. ; Lima, Emília C O ; Azevedo, Ricardo B. ; Morais, Paulo C. ; Lacava, Zulmira G M

Author_Institution

Inst. de Ciencias Biologicas, Univ. de Brasilia

Volume

42

Issue

10

fYear

2006

Firstpage

3605

Lastpage

3607

Abstract

In the present work, some biological effects of the AC magnetic field exposure after magnetoliposome sample treatment were investigated through micronucleus assay and blood and peritoneum cytometry. Data showed that after 5 min exposure AC magnetic field might induce inflammatory reactions, genotoxicity, and cytotoxicity. We conclude that under our experimental conditions magnetohyperthermia experiments may be safely conducted by 3-min AC magnetic field exposure

Keywords

biological effects of fields; cellular effects of radiation; hyperthermia; toxicology; 3 min; 5 min; alternating magnetic field; biological effects; cytometry; cytotoxicity tests; genotoxicity tests; magnetohyperthermia; magnetoliposome; magnetoliposomes; micronucleus; Blood; Bones; Cells (biology); Cobalt; Frequency; Hyperthermia; Magnetic fields; Mice; Nanoparticles; Testing; Alternating magnetic field; cytometry; hyperthermia; inflammation; magnetoliposome; micronucleus;

fLanguage

English

Journal_Title

Magnetics, IEEE Transactions on

Publisher

ieee

ISSN

0018-9464

Type

jour

DOI

10.1109/TMAG.2006.879962

Filename

1704707