• DocumentCode
    769235
  • Title

    T-SPECT: a novel imaging technique for small animal research

  • Author

    Lackas, Christian ; Schramm, Nils U. ; Hoppin, John W. ; Engeland, Uwe ; Wirrwar, Andreas ; Halling, Horst

  • Author_Institution
    Res. Center Julich, Central Inst. for Electron., Julich, Germany
  • Volume
    52
  • Issue
    1
  • fYear
    2005
  • Firstpage
    181
  • Lastpage
    187
  • Abstract
    We present a novel imaging technique based on the translation of the object through the field of view of one or more stationary multipinhole detectors. This new imaging method is called Translatory SPECT or T-SPECT. The benefits of T-SPECT lie in its simple mechanical design along with the potential for imaging otherwise inaccessible regions. The setup of various T-SPECT systems is described and results of numerous simulation studies are presented demonstrating the imaging capabilities of such systems. Specifically, we study T-SPECT with different detector arrangements and compare the performance of T-SPECT with that of SPECT with rotation (R-SPECT). We validate our simulation findings with results from an experiment in which we image a Jaszczak phantom using both R-SPECT and T-SPECT.
  • Keywords
    biomedical imaging; collimators; gamma-ray detection; phantoms; single photon emission computed tomography; Jaszczak phantom; R-SPECT; T-SPECT; Translatory SPECT; collimators; imaging capabilities; molecular imaging; multipinhole detectors; multipinhole tomography; novel imaging technique; numerous simulation studies; small animal research; Animals; Apertures; Collimators; Computational modeling; Detectors; High-resolution imaging; Imaging phantoms; Molecular imaging; Object detection; Optical imaging; High resolution; high sensitivity; molecular imaging; multipinhole tomography; small-animal imaging; translatory SPECT;
  • fLanguage
    English
  • Journal_Title
    Nuclear Science, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9499
  • Type

    jour

  • DOI
    10.1109/TNS.2005.843615
  • Filename
    1417127