DocumentCode
778299
Title
The blueprint for life?
Author
Feitelson, D.G. ; Treinin, M.
Author_Institution
Sch. of Comput. Sci. & Eng., Hebrew Univ., Jerusalem, Israel
Volume
35
Issue
7
fYear
2002
fDate
7/1/2002 12:00:00 AM
Firstpage
34
Lastpage
40
Abstract
One of the greatest scientific discoveries of the twentieth century is the structure of DNA and how it encodes proteins. Current genome projects, especially the Human Genome Project, have sparked interest in the information encoded in DNA, which is often referred to as "the blueprint for life", implying that it contains all the information needed to create life. This interpretation ignores the complex interactions between DNA and its cellular environment, interactions that regulate and control the spatial and temporal patterns of gene expression. Moreover, the particulars of many cellular structures seem not to be encoded in DNA, and they are never created from scratch, rather, each cell inherits templates for these structures from its parent cell. Thus, it is not clear that DNA directly or indirectly encodes all life processes, casting doubt on the belief that we can understand them solely by studying DNA sequences. The paper discusses DNA encoding and computer programming.
Keywords
biocomputing; biotechnology; programming; DNA computing; Human Genome Project; blueprint for life; cellular environment; gene expression; programming; proteins; spatial patterns; temporal patterns; Bioinformatics; Casting; Cells (biology); DNA; Encoding; Gene expression; Genomics; Humans; Proteins; Sequences;
fLanguage
English
Journal_Title
Computer
Publisher
ieee
ISSN
0018-9162
Type
jour
DOI
10.1109/MC.2002.1016899
Filename
1016899
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