• DocumentCode
    797818
  • Title

    Detecting structure in parity binary sequences

  • Author

    Gonzalez, Diego Luis ; Giannerini, Simone ; Rosa, Rodolfo

  • Author_Institution
    Laboratorio di acustica musicale e architettonica, CNR-Fondazione Scuola di S. Giorgio, Venezia, Italy
  • Volume
    25
  • Issue
    1
  • fYear
    2006
  • Firstpage
    69
  • Lastpage
    81
  • Abstract
    In this article, we investigate the possible existence of error-detection/correction mechanisms in the genetic machinery by means of a recently proposed coding strategy. On this basis, we numerically code exons, creating binary parity strings and successively we study their dependence structure by means of rigorous statistical methods (moving block bootstrap, and a new entropy-based method). The results show that parity sequences display complex dependence patterns enforcing the hypothesis of the existence of deterministic error-correction mechanisms grounded on this particular parity coding.
  • Keywords
    binary codes; entropy; error correction codes; error detection codes; genetics; molecular biophysics; statistical analysis; binary parity strings; complex dependence patterns; entropy; error correction; error detection; exons; genetics; moving block bootstrap; parity binary sequences; parity coding; rigorous statistical methods; structure detection; Binary sequences; Biological information theory; Communication systems; DNA; Error correction; Error correction codes; Genetic communication; Information theory; Proteins; Redundancy; Animals; Base Sequence; Computational Biology; DNA; DNA Damage; DNA Repair; Genetic Code; Humans; Information Storage and Retrieval; Models, Genetic; Molecular Sequence Data; Systems Biology; Variation (Genetics);
  • fLanguage
    English
  • Journal_Title
    Engineering in Medicine and Biology Magazine, IEEE
  • Publisher
    ieee
  • ISSN
    0739-5175
  • Type

    jour

  • DOI
    10.1109/MEMB.2006.1578666
  • Filename
    1578666