Title :
All-Silica Hollow-Core Microstructured Bragg Fibers for Biosensor Application
Author :
Passaro, Davide ; Foroni, Matteo ; Poli, Federica ; Cucinotta, Annamaria ; Selleri, Stefano ; Lægsgaard, Jesper ; Bjarklev, Anders Overgaard
Author_Institution :
Dept. of Inf. Eng., Parma Univ., Parma
fDate :
7/1/2008 12:00:00 AM
Abstract :
The possibility to exploit all-silica hollow-core microstructured Bragg fibers to realize a biosensor useful to detect the DNA hybridization process has been investigated. A Bragg fiber recently fabricated has been considered for the analysis performed by means of a full-vector modal solver based on the finite-element method. Since the DNA molecules necessary for the biosensor realization are in aqueous solution, it has been taken into account a microstructured fiber with water-filled holes. The dispersion curve and the confinement loss spectrum have been calculated in order to understand how a biofilm layer on the inner surface of the fiber holes can modify the fundamental mode properties. The numerical analysis results have successfully demonstrated the DNA bio-sensor feasibility in hollow-core Bragg fibers.
Keywords :
Biosensors; DNA; Finite element methods; Optical fiber dispersion; Optical fiber sensors; Optical fibers; Performance analysis; Photonic crystal fibers; Refractive index; Silicon compounds; Biosensor; Bragg fiber; deoxyribonucleic acid (DNA); hollow-core fiber;
Journal_Title :
Sensors Journal, IEEE
DOI :
10.1109/JSEN.2008.926969