Magnetoencephalography cortical source imaging using spherical mapping

This paper proposes a novel approach to enhancing results of magnetoencephalography cortical source imaging. The proposed approach utilizes bell-shaped functions defined on an inflated cortical surface, which has one-to-one correspondence with original tessellated cortical surface. The coefficients of the functions are then determined using sensitivity analysis with conjugate gradient updating scheme. Applications of the approach to a simulation study and a practical experiment have resulted in more stable and smoother brain source distribution, compared to conventional linear inverse approach.