DocumentCode
852174
Title
Genetically modified mesodermal-derived cells for bone tissue engineering
Author
Kofron, Michelle D. ; Zhang, Jeffrey X. ; Lieberman, Jay R. ; Laurencin, Cato T.
Author_Institution
Dept. of Orthopaedic Surg., Univ. of Virginia Health Syst., Charlottesville, VA, USA
Volume
22
Issue
5
fYear
2003
Firstpage
57
Lastpage
64
Abstract
Alternatives to autografts and allografts for accelerated healing of skeletal defects. This article discusses the use of cells, isolated from tissues originating from the mesodermal germ layer and genetically modified to express bone morphogenetic protein, for bone tissue engineering applications.
Keywords
biological tissues; bone; cellular biophysics; molecular biophysics; orthopaedics; patient treatment; proteins; tissue engineering; accelerated healing; bone morphogenetic protein; bone tissue engineering; bone tissue engineering applications; genetically modified mesodermal-derived cells; mesodermal germ layer; skeletal defects; Acceleration; Biological materials; Bone tissue; Capacitive sensors; Genetic engineering; In vivo; Mechanical factors; Polymers; Skin; Stress;
fLanguage
English
Journal_Title
Engineering in Medicine and Biology Magazine, IEEE
Publisher
ieee
ISSN
0739-5175
Type
jour
DOI
10.1109/MEMB.2003.1256273
Filename
1256273
Link To Document