• DocumentCode
    866658
  • Title

    Refining Phylogenetic Trees Given Additional Data: An Algorithm Based on Parsimony

  • Author

    Wu, Taoyang ; Moulton, Vincent ; Steel, Mike

  • Author_Institution
    Dept. of Comput. Sci. & Sch. of Math. Sci., Univ. of London, London
  • Volume
    6
  • Issue
    1
  • fYear
    2009
  • Firstpage
    118
  • Lastpage
    125
  • Abstract
    Given a set X of taxa, a phylogenetic X-tree T that is only partially resolved, and a collection of characters on X, we consider the problem of finding a resolution (refinement) of T that minimizes the parsimony score of the given characters. Previous work has shown that this problem has a polynomial time solution provided certain strong constraints are imposed on the input. In this paper we provide a new algorithm for this problem, and show that it is fixed parameter tractable under more general conditions.
  • Keywords
    biology computing; trees (mathematics); parsimony score; phylogenetic X-tree; phylogenetic trees; polynomial time solution; Combinatorial algorithms; Life and Medical Sciences; Algorithms; Computational Biology; Evolution; Models, Genetic; Phylogeny;
  • fLanguage
    English
  • Journal_Title
    Computational Biology and Bioinformatics, IEEE/ACM Transactions on
  • Publisher
    ieee
  • ISSN
    1545-5963
  • Type

    jour

  • DOI
    10.1109/TCBB.2008.100
  • Filename
    4626947