DocumentCode
945123
Title
Grid-Added Value to Address Malaria
Author
Breton, V. ; Jacq, N. ; Kasam, V. ; Hofmann-Apitius, M.
Author_Institution
Univ. Blaise Pascal, Aubiere
Volume
12
Issue
2
fYear
2008
fDate
3/1/2008 12:00:00 AM
Firstpage
173
Lastpage
181
Abstract
Through this paper, we call for a distributed, Internet- based collaboration to address one of the worst plagues of our present world, malaria. The spirit is a nonproprietary peer-production of information-embedding goods. And we propose to use the grid technology to enable such a worldwide "open-source" like collaboration. The first step toward this vision has been achieved during the summer 2005 on the enabling grids for E-scienceE (EGEE) grid infrastructure where 42 million ligands were docked for a total amount of 80 CPU years in 6 weeks in the quest for new drugs. The impact of this first deployment has significantly raised the interest of the research community so that several laboratories all around the world expressed interest to propose targets for a second large-scale deployment against malaria.
Keywords
Internet; diseases; drug delivery systems; genetics; grid computing; medical computing; Internet-based collaboration; disease monitoring; drug discovery; genomics; grid computing; grid infrastructure; grid technology; malaria; virtual screening; Computing grid; computing grid; malaria; virtual screening by docking; Antimalarials; Computational Biology; Cooperative Behavior; Database Management Systems; Drug Design; Epidemiologic Methods; Humans; Information Dissemination; Internationality; Internet; Malaria;
fLanguage
English
Journal_Title
Information Technology in Biomedicine, IEEE Transactions on
Publisher
ieee
ISSN
1089-7771
Type
jour
DOI
10.1109/TITB.2007.895930
Filename
4358875
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