• DocumentCode
    952116
  • Title

    An Automatic Translation of SBML into Beta-Binders

  • Author

    Ciocchetta, Federica ; Priami, Corrado ; Quaglia, Paola

  • Author_Institution
    Univ. of Edinburgh, Edinburgh
  • Volume
    5
  • Issue
    1
  • fYear
    2008
  • Firstpage
    80
  • Lastpage
    90
  • Abstract
    A translation of systems biology markup language (SBML) into a process algebra is proposed in order to allow the formal specification, the simulation, and the formal analysis of biological models. Beta-binders, a language with a quantitative stochastic extension, is chosen for the translation. The proposed translation focuses on the main components of SBML models, as species and reactions. Furthermore, it satisfies the compositional property, that is, the translation of the whole model is obtained by composing the translation of the subcomponents. An automatic translator tool of SBML models into Beta-binders has been implemented as well. Finally, the translation of a simple model is reported.
  • Keywords
    biology computing; hypermedia markup languages; SBML; automatic translation; beta-binders; systems biology markup language; Process algebras; Systems Biology Markup Language (SBML); biological systems; modeling; systems biology; translation tool; Algorithms; Catalysis; Computer Simulation; Kinetics; Metabolic Networks and Pathways; Models, Biological; Programming Languages; Receptors, Cholinergic; Stochastic Processes; Systems Biology;
  • fLanguage
    English
  • Journal_Title
    Computational Biology and Bioinformatics, IEEE/ACM Transactions on
  • Publisher
    ieee
  • ISSN
    1545-5963
  • Type

    jour

  • DOI
    10.1109/TCBB.2007.70219
  • Filename
    4359877