DocumentCode
952116
Title
An Automatic Translation of SBML into Beta-Binders
Author
Ciocchetta, Federica ; Priami, Corrado ; Quaglia, Paola
Author_Institution
Univ. of Edinburgh, Edinburgh
Volume
5
Issue
1
fYear
2008
Firstpage
80
Lastpage
90
Abstract
A translation of systems biology markup language (SBML) into a process algebra is proposed in order to allow the formal specification, the simulation, and the formal analysis of biological models. Beta-binders, a language with a quantitative stochastic extension, is chosen for the translation. The proposed translation focuses on the main components of SBML models, as species and reactions. Furthermore, it satisfies the compositional property, that is, the translation of the whole model is obtained by composing the translation of the subcomponents. An automatic translator tool of SBML models into Beta-binders has been implemented as well. Finally, the translation of a simple model is reported.
Keywords
biology computing; hypermedia markup languages; SBML; automatic translation; beta-binders; systems biology markup language; Process algebras; Systems Biology Markup Language (SBML); biological systems; modeling; systems biology; translation tool; Algorithms; Catalysis; Computer Simulation; Kinetics; Metabolic Networks and Pathways; Models, Biological; Programming Languages; Receptors, Cholinergic; Stochastic Processes; Systems Biology;
fLanguage
English
Journal_Title
Computational Biology and Bioinformatics, IEEE/ACM Transactions on
Publisher
ieee
ISSN
1545-5963
Type
jour
DOI
10.1109/TCBB.2007.70219
Filename
4359877
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