Detection of noncharged organic substances by new measurement method using a lipid membrane sensor

Author

Naito, Yoshinobu ; Ikezaki, Hidekazu ; Taniguchi, Akira ; Toko, Kiyoshi

Author_Institution

Anritsu Corp. Res. Lab., Kanagawa, Japan

Volume

4

Issue

3

fYear

2004

fDate

6/1/2004 12:00:00 AM

Firstpage

279

Lastpage

283

Abstract

This paper reports a new measurement method to detect ppb levels of noncharged organic substances using lipid/polymer membrane sensors. Noncharged organic substances have large influences on the adsorption of positively-charged lipids to negatively-charged membranes. Organic solvents (trichloroethylene) and endocrine disrupting chemicals (di-2-ethylhexylphthalate) were detected by utilizing the sensor output, which is the change of membrane potential caused by interactions among the lipid membrane, noncharged organic substances, and lipids in solution. This new potentiometric method has a possibility of detection of a trace amount of noncharged toxic substances.

Keywords

chemical sensors; lipid bilayers; polymers; di-2-ethylhexylphthalate; endocrine disrupting chemicals; lipid membrane sensors; negatively-charged membranes; noncharged organic substances; noncharged toxic substances; organic solvents; polymer membrane sensors; positively-charged lipids; potentiometry; trichloroethylene; Biomembranes; Chemical analysis; Chemical sensors; Electrodes; Endocrine system; Intelligent sensors; Lipidomics; Organic chemicals; Polymers; Solvents; Adsorption; lipid/polymer membrane; noncharged organic substances;

fLanguage

English

Journal_Title

Sensors Journal, IEEE

Publisher

ieee

ISSN

1530-437X

Type

jour

DOI

10.1109/JSEN.2004.827218

Filename

1294905