• DocumentCode
    983069
  • Title

    Real-time detection of microbial contamination

  • Author

    Kim, Hea-Young ; Estes, Cory R. ; Duncan, Andrew G. ; Wade, Brad D. ; Cleary, Florine C. ; Lloyd, Christopher R. ; Ellis, Walther R., Jr. ; Powers, Linda S.

  • Author_Institution
    Nat. Center for the Design of Molecular Function, Utah State Univ., Logan, UT, USA
  • Volume
    23
  • Issue
    1
  • fYear
    2004
  • Firstpage
    122
  • Lastpage
    129
  • Abstract
    We demonstrate the utility of this molecular engineering-based capture and detection technology for use in homeland defense. This capture technology can be placed on a "chip" where each section contains a different ligand. Intrinsic fluorescence is then used to monitor the binding of biomaterial in each section containing a ligand and determines the nature of the biomaterial (e.g., live bacterial cells, dead cells, spores, or tryptophan/tyrosine containing protein molecules).
  • Keywords
    biohazards; biosensors; fluorescence; molecular biophysics; proteins; terrorism; biomaterial; detection technology; fluorescence; homeland defense; microbial contamination; molecular engineering-based capture; protein molecules; real-time detection; Cardiac disease; Contamination; DNA; Fluorescence; Fungi; Laboratories; Microorganisms; Optical microscopy; Postal services; Production; Bacteria; Biosensing Techniques; Bioterrorism; Colony Count, Microbial; Environmental Microbiology; Environmental Monitoring; Equipment Design; Microbiological Techniques; Online Systems; Security Measures; Viruses;
  • fLanguage
    English
  • Journal_Title
    Engineering in Medicine and Biology Magazine, IEEE
  • Publisher
    ieee
  • ISSN
    0739-5175
  • Type

    jour

  • DOI
    10.1109/MEMB.2004.1297183
  • Filename
    1297183