بررسي ميزان همراهي ضايعات پوستي و دهاني ليكن پلان در بيماران مراجعه كننده به مركز آموزشي درماني لقمان حكيم در تابستان 1381

The prevalence of coincide dermal and oral lesions of lichen pIanus (Research)

Lichen planus is a common chronic inflammatory epidermal and mucosal disease involving skin, mucosa and both sometimes, the cause of with is poorly understood. Due to the importance and itʹs prevalence, this strudy was carried out in order to assess the association of oral and dermal lesions in patient referring to dermatology clinic of Tehran Razi Hospital during summer of 2001. A total of 101 patient with dermal or oral lesions of lichen planus were selected among 6510 patients had referred to Tehran Razi Hospital - dermatology clinic in this descriptive study. The selected cases were subjected to further and exact clinical examination along with interview, while in doubtful samples, the conducted histopatologic tests obtained by biopsy were used for the evaluation. A questionnaire was completed for each patient after taking history and physical examination including history of systemic diseases, intervening drug usage, smoking habits, presence of oral and dermal lesions, time passed from the appearance of dermal and oral lesions and the treatment period, oral lesions signs and the patients complaint, the position, the way and rate of distribution, oral lesion history as well as existence of amalgam restoration beside the lesion. The study revealed the 17.89 percent association of oral and dermal lesions in the study population, wile dermal lesion were observed in 80 percent of patints and oral lesions in 2.1 percent. The incidence of lichen planus oral lesion was slightly higher in females in comparsion to males (21.3 percent in females and 18.8 percent in males). 15.8 percent of oral LP patients were smoker and just one had history of pipe or tobacco smoking. Patients with dermal lichen planus reported a time between 1-6 months passing from their appearance, while the cases with oral lichen planus were unaware of the beginning time of lesions. The most reported symptom of oral lichen planus in the study population was burn of the place while the buccal mucosa was the place with the most common site of involvement and reticular form was the form of highly prevalence. There was no significant statistical relationship between smoking and amalgam restoration as risk factors and oral lichen planus appearance as well as with systemic disease such as diseases of liver, connective tissue, hypertension, diabetes mellitus, bone marrow transplantation and the usage of interventional drugs. High incidence of dermal and oral lichen planus association revealed throughout the study calls the attention for complete systemic examinations of the patients. As this study was carried out in the dermatology clinic, it seem that other studies in the dental schools as well as throughout the public will be of necessity and importance to verify the results.