ارزيابي خصوصيات بيماران مبتلا به پمفيگوس بستري شده در بخش پوست بيمارستان سينا همدان از سال 1371 لغايت 1374

Evaluation of Characteristics of Pemphigus Patients Hospitalized in the Dermatology Ward of Sina Hospital Hamadan - Iran During 1992-1995

Pemphigus describe a group of autoimmune disease characterized by blisters and erosions of the skin and mucous membrane , acantholysis and autoantibodies against epidermal cell surface components. The aim of this study was assessment of pemphigus patients hospitalized in the dermatology ward of Sina hospital Hamadan. The research was descriptive ʹretrospective study and was done on the base of information that obtained from 37 pemphigus patientsʹ file hospitalized in Sina hospital during 1992-1995. In this study 23(62.2%) patients were female and 14(37.8%1 patients were male and most of the patients were in the age of 41-50 years. Oral lesion was seen in the 83% patients that in one third of the patients (32.4%) was the initial presentation. Relapse in this study was (29.7%). Death occurred in four patients (3 women and I man) and septicemiaʹ was the most common cause of death. The most common from of pathology was pemphigus vulgaris. The average time between beginning of the disease and admission time was 103 days. This study showed that pemphigus was more common in women than men, also relapse of pemphigus in this study was more than the other studies which was done in other countries.