بررسي 8 ساله ي بدخيمي هاي خوني در بيمارستان دكتر بهشتي زنجان (78-1370)

Background: Blood malignancies are among important blood diseases. To determine the epidemiology of blood malignancies a descriptive study was carried out in Zanjan Beheshti hospital from 1993 to 2000. Materials and Methods: Over a period of 8 years patients with blood malignancies were diagnosed by laboratory methods using existing data in their files. Hematological indices such as CBC, Hb, Het, study of blood smear were carried out for all patients and bone marrow aspiration was conducted for suspected patients. The type of malignancy was diagnosed by morphological findings, cytochemical staining and flow cytometry. Results: The results showed that out of 184 patients, 68 (37%) were ALL, 47 (25.5%) AML, 23(12.5%) CML, 23 (12.5%) CLL,14 (7.6%) multiple myeloma. The most prevalent types of all were L, and L2 M3, M4 and M2 respectively. In all types of blood malignancies the men outnumbered the women. The most common clinical symptoms in acute leukemic patients were weakness (75%) and fever (62.5%) and in CML cases abdominal pain (57.1%). In labratory finding concerning acute leukemic patients, 49.4% had blood cell count under 10000. Conclusion: Above findings are somehow different from other studies in terms of prevalent leukemic patient type and demographic characteristics. Complementary studies concerning the present differences are recommended.