بررسي ارزش تشخيصي گلوتاتيون - S ترانسفرازملا به عنوان يك ماركر براي سريان هاي دستگاه گوارش

A STUDY OF THE DIAGNOSTIC VALUE OF GLUTATHIONE- S-TRANSFERASE(Mio) AS A MARKER FOR GASTROINTESTINAL MALIGNANCIES

Recently, tumor markers are important for diagnosis and follow up of some malignancies . Glutathione -s- transferase is an enzyme that may be a tumor marker in gastrointestinal cancers, especially esophageal and gastric carcinomas. Measurment of serum activity of glutathione - s- transferase p in 42 normal volunteers, 29 esophageal cancer patients and 28 stomach cancer patients was done. This study was descriptive . Serum activity of glutathione -s- transferance p increased significantly in malignant patients as compared to normal volunteers. G.S.T. P increases in esophageal and stomach cancer and can be a tumor marker for diagnosis and follow up of these patients .