بررسي ويروس پاپيلوماي انساني در زگيل هاي آيوژينتال با روش PCR

Evaluation of human papilloma viruses in anogenital warts using PCR method

Background and aim: Anogenital wart is a common skin disease and 1.3 million new cases are diagnosed in the US each year. About one percent of sexually active adults suffer from anogenital warts. This study was performed to evaluate human papilloma viruses (HPV) in anogenital warts using Polymerase Chain Reaction (PCR) method in patients admitted to the Skin Clinics of Skin Research Center, Shahid Beheshti Univesity of Medical Sciences. Materials and Methods: This cross sectional study was performed on 32 patients with anogenital warts, whose clinical diagnosis was confirmed by histopathologic examination. Biopsy specimens of the patients were evaluated by PCR method and virus type was determined. Results: In 12 (37%) patients HPV infection was confirmed using PCR method. The distribution of patients among infections with high-and low-risk HPVs was not different. There was no correlation between clinical features and HPV type. Conclusion: Controlled studies with larger sample sizes are recommended.