خصوصيات باليني و دموگرافيك بيماران مسموم با بنزوديازپين ها بستري در بخش مسمومين بيمارستان نور و علي اصغر اصفهان سال 81 - 1380

Clinical and Demographic Characteristics of Benzodiazepines Poisoning in Toxicology Center of Isfahan: 2001-2002

Introduction and Objectives: Benzodiazepines have enjoyed popularity in the public and among physicians. These drugs have various sedative-hypnotic, anxiolytic and anticonvulsant properties. A number of these agents are available for use in the United States This study aimed at determining the distribution frequency of benzodiazepines poisoning with regard to clinical and demographic characteristics Materials and Methods: In this one-year prospective study (Oct 2001-0ct 2002), all the poisoned patients, who referred to toxicology center of Noar and Aliasghar were examined There were 3250 cases Variables such as age, sex, poisoning agents and route, duration of hospitalization, clinical presentations, respiratory support and mortality were included in thiS study. Results: There were 402 cases of benzodiazepine poisoning, of which 211 cases (524 percent) were male and the others were female. Most of the cases (5108 percent) were in 21-30 age group. Hospital stay was 1 day (96.5 percent). Diazepam overdose was mare than other drugs (45.7). Poisoning route was injection in all cases Tracheal intubation was necessary for 5 patients (1.3 percent) and one of them (02 percent) underwent mechanical ventilation The most common clinical presentations were neurological and eNS sings and symptoms (49 percent) Mortality rate was 0.2 percent (one case) Conc/usion:According to this study, no Injury of body systems IS seen with benzodiazepine overdose This finding IS comparable with the to other related studies Benzodiazepme overdose IS common and are easily available. However it causes relatively high incidence of psychological disorders. Results necessitate warning against these agents.