تاثير يك دوره تمرين هوازي بر ميزان لپتين ، كورتيزول و تستوسترون سرم مردان چاق و لاغر

The effects of aerobic training on Ieptin, cortisol and serum testosterone levels in obese and lean men

The purpose of this study was to determine the effects of aerobic training on leptin, cortisol and serum testosterone levels in obese and lean men. To this end healthy and volunteers men, (age,30±5 years) were asked to complete a questionnaire including individual characteristics, health history, amount of physical activity and smoking. Body mass index was measured using the body composition analyzer and 40 untrained people were selected and divided in two groups: 20subjects (weight: 96/8±15!9kg, height: I71/5±12/3cm. age: 30±5 years, BMI: 32/3±2/l kg/mʹ) in obese group and 20 subjects (weight: 57±3/3kg. height: 177±4/47 em, age: 30±5 years, BMI: 18/1±0/58 kg/mʹ) in lean group. To measure the leptin, cortisol and serum testosterone levels by the radioimmunoassay (RIA) method, blood samples were taken before having breakfast and 2 days before aerobic training program. Then both groups performed aerobic training including running at 65-85% of individual maximum heart rate on treadmill in 2 consecutive months, 3 sessions a week, and 30 minutes per session. Then blood samples were taken after the training period and all parameters were measured again. The analysis of data before and after aerobic training using t- test showed significant decreases in weight (p= 0.000), BMI (p~O.012) leptin (p~O.OOO) and a significant increase in cortisol (p~0.027) for obese group. Also a significant decrease in leptin (p~0.004) and significant increases in BMI (p=0.008), cortisol (p=0.070) in lean group. Moreover, when data were compared between obese and lean groups, significant differences were found for leptin(p=0.000).testosterone(p=O.009), BMI(p=O.OOO)and weight(p~O.OOO.( Based on the results, aerobic training via altering some hormones including leptin, cortisol, and testosterone has an important role in regulation of body weight. Meanwhile, the mechanisms that aerobic training regulates body weight might be different in obese and lean groups.