عنوان مقاله :
نقش ماتريكس متالوپروتئينازها در ايجاد و بهبود فيبروز سيروز كبد
عنوان به زبان ديگر :
Matrix Metalloproteinaseʹs Role in Producing and Curing
of Liver Fibrosis
پديد آورندگان :
رباني، وحيده نويسنده پژوهشكده رويان- مركز تحقيقات علوم سلولي جهاد دانشگاهي- گروه سلول هاي بنيادي و زيست شناسي تكويني- تهران- ايران RABANI, V. , بهاروند، حسين نويسنده گروه زيست شناسي تكويني دانشگاه علم و فرهنگ ،تهران BAHARVAND, H.
كليدواژه :
Hepatic Stellate Cells , سلول هاي بنيادي , Fibrosis , سلول هاي ستاره اي كبد , Stem cells , Matrix Metalloprotelnase , فيبروز , ماتريكس متالوپروتئيناز , زيست شناسي
چكيده لاتين :
Matrix
metalloproteinases are a zinc and calcium dependent endopeptidase family that are
expressed in Injured tissue such as cardiovascular or hepatic disease. Complex efforts of this
enzymes on the extra cellular matrix structure is related to up and down regulation of them
and their tissue inhibitors. Configuration of extra cellular matrix during pathogenesis, curing
and development is affected by two key mechanisms: matrix metalloproteinase and hepatic
stellate cell activity. The important role of these enzymes on liver injuries and regeneration
are indicated when their effects on migration of bone marrow stem cells and hepatic stem
cells was discoverd
كلمات كليدي :
#تست#آزمون###امتحان
