تاثير اكسيژن اضافي در كاهش تهوع و استفراغ پس از اعمال جراحي پستان

Effects of Supplemental Oxygen for Prevention of Nausea And Vomiting After Breast Surgery

Introduction: Postoperative nausea and vomiting (PONV) is the most frequent side effect after anesthesia, occurring in 20-70% of patients during the first 24 h after surgery. Some studies indicate that an increase in inspired oxygen concentration can decrease incidence of PONV. In this study, we tried to evaluate the effects of supplemental 100% oxygen on PONV in patients undergoing breast surgery. Materials & Methods: In a clinical double-blind study, 60 patients receiving standardized halothane anesthesia were randomly assigned to the following two groups: group 30 (30% oxygen in air) and group 100 (100% oxygen). Postoperative Accepted: 22 Nov, 2009) nausea and vomiting were assessed over the first 24 h after surgery in both the groups. Findings: There was a significant difference between the two groups.( PONV was 30% in group 100 versus 64% in group 30).(p value <0.05) Discussion & Conclusion: This study showed that intraoperative high oxygen concentration effectively prevents PONV after breast surgery and reduces the need for antiemetic drugs in these groups of patients.