عنوان مقاله :
شناسايي تركيبات شيميايي روغن فرار دو گياه آويشن شيرازي (Zataria multiflora Boiss.) و مرزنگوش (Origaunum majorana L.) و بررسي اثرات ضدويروسي آنها
عنوان به زبان ديگر :
Chemical Compositions and Antiviral Effects of the Essential Oil of Zataria multiflora Boiss. and Origanum majorana L.
پديد آورندگان :
خانوي، مهناز نويسنده دانشگاه علوم پزشكي تهران,دانشكده داروسازي; Khanavi , M. , نوروزي، مهدي نويسنده دانشكده پزشكي- دانشگاه علوم پزشكي تهران Norouzi, M. , طباطبايي، حميده نويسنده دانشكده بهداشت- دانشگاه علوم پزشكي تهران Tabatabaei , H. , صالحي نوده، عليرضا نويسنده دانشكده بهداشت و انيستيتو تحقيقات بهداشتي، دانشگاه علوم پزشكي تهران Noudeh, A.. , برزگرصفوي، سهيلا نويسنده دانشكده داروسازي، دانشگاه علوم پزشكي تهران Safavi , S. , شفيعي، عباس نويسنده دانشكده داروسازي-دانشگاه علوم پزشكي -دانشگاه تهران Shafiei, A.
اطلاعات موجودي :
فصلنامه سال 1388 شماره 33
كليدواژه :
ZATARIA MULTIFLORA , Organum majorana , روغن فرار , ويروس , سلول Hela
چكيده لاتين :
Background: Zataria multiflora Boiss. is considered as an annual plant endemic in south of Iran. Origanum majorana L. is one of the most famous medicinal and nutritional herbs growing in the temperate zones of south Europe. These two have been used as carminative, anti-inflammatory, antiviral, bronchodilator and expectorant in traditional medicine of Iran and European countries.
Objective: In the current study, chemical composition and antiviral effect of the essential oil of Z. multiflora and O. majorana are investigated.
Methods: Composition of the essential oil samples obtained by hydrodistillation of the aerial parts of Z. multiflora and O. majorana (Lamiaceae) were analyzed by GC and GC/MS. Antiviral effect of the oils were investigated on Herpese simplex separately.
Results: Twenty-four components in the oil of Z. multiflora with thymol (38%), carvacrol (34.96%) and para-cymene (7.17%) as the major constituents were identified. Twenty-seven components in the oil of O. majorana were recognized, whereas terpinene-4-ol (36.2%), para-cymene (16.3%) and g-terpinene (7.31%) were the main components. The concentration of 1/10000 of each oil was added to Hela cells contained with HSV-I. The growth of the organism was not inhibited at this concentration of the oils.
Conclusion: In this research 98.62% and 96.72% of the essential oil of Z. multiflora and
O. majorana were determined. Both essential oils were characterized by a high amount of oxygenated compounds (85.33% and 60.3% respectively). Where as the concentration more than 1/10000 of the oils were citotoxic for Hela cells, more study and different methods is needed to investigate antiviral effects of these two oils
عنوان نشريه :
گياهان دارويي
عنوان نشريه :
گياهان دارويي
اطلاعات موجودي :
فصلنامه با شماره پیاپی 33 سال 1388
كلمات كليدي :
#تست#آزمون###امتحان