اثرات مصرف آب هويج غني شده با بتاكاروتن بر سطح ليپيدهاي سرم در بيماران مبتلا به ديابت نوع 2

Effects of B-carotene-fortified carrot juice on the lipid profile in type-2 diabetes patients

Background and Objectives: Hyperlipedemia is a health problem in type-2 diabetes patients. This study was designed to investigate the effects of carrot juice fortified with B-carotene on the blood lipids in these patients. Subject and Methods: This controlled randomized double-blind clinical trial was performed on 44 patients with type 2 diabetes. They were randomly divided into two groups receiving, daily for 8 weeks, either 200 ml carrot juice fortified with 10 mg B-carotene (group A) or 200 ml ordinary carrot juice (group B). All the subjects would drink the juice (exchanged for one serving of bread) at lunch. Twenty-four hour dietary recalls were done on 3 consecutive days and 6 alternate days by a nutritionist at the beginning and the end of the period. Initial and final fasting blood glucose, B-carotene, and lipids were also measured. The dietary data were analyzed using Nutritionist IV and statistical analysis was done using SPSS 11.5. Results: The serum level of B-carotene increased and that of total cholesterol and triglyceride, as well as the LDL-C/HDL-C and TC/HDL-C ratios, decreased significantly in group A as compared to group B. The treatments did not affect HDL-C or glucose concentrations in either group. Conclusion: Daily consumption of both 200 ml carrot juice fortified with 10 mg B-carotene and ordinary carrot juice for 8 weeks brings about desirable changes in some of the blood lipids in type-2 diabetic subjects without any change in the serum glucose level, although fortified carrot juice is more effective. Such an intervention may prevent hyperlipedemia in these patients.