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1
Discovery and optimization of novel, non-steroidal glucocorticoid receptor modulators
2
Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase
3
Discovery and optimization of substituted piperidines as potent, selective, CNS-penetrant α4β2 nicotinic acetylcholine receptor potentiators
4
Discovery and parallel synthesis of a new class of cathepsin k inhibitors
5
Discovery and preclinical studies of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737), an in vivo active potent VEGFR-2 inhibitor
6
Discovery and preliminary evaluation of 5-(4-phenylbenzyl)oxazole-4-carboxamides as prostacyclin receptor antagonists
7
Discovery and preliminary structure–activity relationship studies of novel benzotriazine based compounds as Src inhibitors
8
Discovery and SAR development of 2-(phenylamino) imidazolines as postacyclin receptor antagonists
9
Discovery and SAR development of thienopyridones: A class of small molecule AMPK activators
10
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents
11
Discovery and SAR of 2-(1-propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide: A potent inhibitor of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer Original Research Article
12
Discovery and SAR of 2-amino-5-(thioaryl)thiazoles as potent and selective Itk inhibitors
13
Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors
14
Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer’s disease
15
Discovery and SAR of 4-amino-2-biarylbutylurea MCH 1 receptor antagonists through solid-phase parallel synthesis
16
Discovery and SAR of biaryl piperidine MCH1 receptor antagonists through solid-phase encoded combinatorial synthesis
17
Discovery and SAR of diarylsulfide cyclopropylamide LFA-1/ICAM-1 interaction antagonists
18
Discovery and SAR of hydrazide antagonists of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor type 1 (PAC1-R)
19
Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind β-secretase in a N-terminal 10s-loop down conformation
20
Discovery and SAR of new benzazepines as potent and selective 5-HT2C receptor agonists for the treatment of obesity
21
Discovery and SAR of novel [ and ]Naphthyridines as potent inhibitors of spleen tyrosine kinase (SYK)
22
Discovery and SAR of novel 4-thiazolyl-2-phenylaminopyrimidines as potent inhibitors of spleen tyrosine kinase (SYK)
23
Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors
24
Discovery and SAR of Org 24598—A Selective Glycine Uptake Inhibitor
25
Discovery and SAR of oxindole–pyridine-based protein kinase B/Akt inhibitors for treating cancers
26
Discovery and SAR of potent, orally available and brain-penetrable 5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen- and 4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen derivatives as neuropeptide Y Y5 receptor antagonists
27
Discovery and SAR of trisubstituted thiazolidinones as CCR4 antagonists
28
Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors
29
Discovery and SAR studies of novel GlyT1 inhibitors
30
Discovery and SAR study of novel dihydroquinoline containing glucocorticoid receptor ligands
31
Discovery and SAR study of novel dihydroquinoline-containing glucocorticoid receptor agonists
32
Discovery and Significance of Eclogite-Granitoid Belts in Northwest China
33
Discovery and stereoselective synthesis of the novel isochroman neurokinin-1 receptor antagonist ‘CJ-17,493’ Original Research Article
34
Discovery and Structural Characterization of a New Inhibitor Series of HIV-1 Nucleocapsid Function: NMR Solution Structure Determination of a Ternary Complex Involving a 2:1 Inhibitor/NC Stoichiometry
35
Discovery and structure–activity relationship analysis of Staphylococcus aureus sortase A inhibitors Original Research Article
36
Discovery and structure–activity relationship of 2-phenyl-oxazole-4-carboxamide derivatives as potent apoptosis inducers
37
Discovery and structure–activity relationship of coumarin derivatives as TNF-α inhibitors
38
Discovery and structure–activity relationship of N-phenyl-1H-pyrazolo[3,4-b]quinolin-4-amines as a new series of potent apoptosis inducers Original Research Article
39
Discovery and structure–activity relationship studies of a novel and specific peptide motif, pro-X-X-X-asp-X, as a platelet fibrinogen receptor antagonist Original Research Article
40
Discovery and structure–activity relationship studies of indole derivatives as liver X receptor (LXR) agonists
41
Discovery and structure–activity relationships of 2-benzylpyrrolidine-substituted aryloxypropanols as calcium-sensing receptor antagonists
42
Discovery and structure–activity relationships of new steroidal compounds bearing a carboxy-terminal side chain as androgen receptor pure antagonists
43
Discovery and structure–activity relationships of novel selective norepinephrine and dual serotonin/norepinephrine reuptake inhibitors
44
Discovery and structure–activity relationships of novel sulfonamides as potent PTP1B inhibitors
45
Discovery and structure-activity studies of a novel series of pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors
46
Discovery and study of dinosaurs from Spain: The contribution of Albert F. de Lapparent
47
Discovery and synthesis of a novel and selective drug-like P2X1 antagonist
48
Discovery and synthesis of a novel series of quinoline-based thrombin receptor (PAR-1) antagonists
49
Discovery and synthesis of a potent sulfonamide ETB selective antagonist
50
Discovery and synthesis of novel phosphine-based ligands for aryl aminations
51
Discovery and synthesis of tetrahydroindolone derived semicarbazones as selective Kv1.5 blockers
52
Discovery and synthesis of tetrahydroindolone-derived carbamates as Kv1.5 blockers
53
Discovery and the structural basis of a novel p21-activated kinase 4 inhibitor
54
Discovery and Understanding of Transition-Metal-Catalyzed Aromatic Substitution Reactions
55
Discovery and validation of new protein biomarkers for urothelial cancer: A prospective analysis: Theodorescu D, Wittke S, Ross MM, Walden M, Conaway M, Just I, Mischak H, Frierson HF, Department of Molecular Physiology, Mellon Prostate Cancer Institute,
56
Discovery from combinatorial heterogeneous catalysis: A new class of catalyst for ethane oxidative dehydrogenation at low temperatures Original Research Article
57
Discovery Learning Strategy in Geographical Education: A Sample of Lesson Design
58
Discovery learning, representation, and explanation within a computer-based simulation: finding the right mix
59
Discovery limits in prospective studies
60
Discovery limits in prospective studies
61
Discovery of (−)-6-[2-[4-(3-fluorophenyl)-4-hydroxy-1-piperidinyl]-1-hydroxyethyl]-3,4-dihydro-2(1H)-quinolinone—A potent NR2B-selective N-methyl d-aspartate (NMDA) antagonist for the treatment of pain
62
Discovery of (2S)-N-[(1R)-2-[4-cyclohexyl-4-[[(1,1-dimethylethyl)amino]carbonyl]-1-piperidinyl]-1-[(4-fluorophenyl)methyl]-2-oxoethyl]-4-methyl-2-piperazinecarboxamide (MB243), a potent and selective melanocortin subtype-4 receptor agonist
63
Discovery of (naphthalen-4-yl)(phenyl)methanones and N-methyl-N-phenylnaphthalen-1-amines as new apoptosis inducers using a cell- and caspase-based HTS assay
64
Discovery of (R)-1-[2-Hydroxy-3-(4-hydroxy-phenyl)-propyl]-4-(4-methyl-benzyl)-piperidin-4-ol: A Novel NR1/2B Subtype Selective NMDA Receptor Antagonist
65
Discovery of (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S,Z)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide (BMS-433796): A γ-secretase inhibitor with Aβ lowering activity in a transgenic mouse model of Alzheimer’s dis
66
Discovery of (Z)-2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives active against Haemonchus contortus and Ctenocephalides felis (cat flea)
67
Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor
68
Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays
69
Discovery of +(2-{4-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethoxy]phenyl}-cyclopropyl)acetic acid as potent and selective αvβ3 inhibitor: Design, synthesis, and optimization Original Research Article
70
Discovery of 1-(4-phenoxypiperidin-1-yl)-2-arylaminoethanone stearoyl-CoA desaturase 1 inhibitors
71
Discovery of 1,1-dioxo-1,2,6-thiadiazine-5-carboxamide derivatives as cannabinoid-like molecules with agonist and antagonist activity Original Research Article
72
Discovery of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid diamides that increase CFTR mediated chloride transport
73
Discovery of 1,3-disubstituted-1H-pyrrole derivatives as potent Melanin-Concentrating Hormone Receptor 1 (MCH-R1) antagonists
74
Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors Original Research Article
75
Discovery of 1,7-cyclized indoles as a new class of potent and highly selective human β3-adrenergic receptor agonists with high cell permeability Original Research Article
76
Discovery of 17,18O-rich material from meteorite by direct-imaging method using stigmatic-SIMS and 2D ion detector
77
Discovery of 1-amino-4-phenylcyclohexane-1-carboxylic acid and its influence on agonist selectivity between human melanocortin-4 and -1 receptors in linear pentapeptides
78
Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. Part 1: Structure–activity relationships of the 1- and 3-positions
79
Discovery of 2,3,5-trisubstituted pyridine derivatives as potent Akt1 and Akt2 dual inhibitors
80
Discovery of 2,3-diaryl-1,3-thiazolidin-4-ones as potent anti-HIV-1 agents
81
Discovery of 2,4,6-trisubstituted N-arylsulfonyl piperidines as γ-secretase inhibitors
82
Discovery of 23 Natural Tubulysins from Angiococcus disciformis An d48 and Cystobacter SBCb004 Original Research Article
83
Discovery of 2-amino-6-carboxamidobenzothiazoles as potent Lck inhibitors
84
Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56lck inhibitors
85
Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening
86
Discovery of 2-Phenyl-3-sulfonylphenyl-indole derivatives as a new class of selective COX-2 inhibitors Original Research Article
87
Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: Synthesis and SAR studies
88
Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-α production Original Research Article
89
Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13
90
Discovery of 3,5-bis(trifluoromethyl)benzyl l-arylglycinamide based potent CCR2 antagonists
91
Discovery of 3-acetyl-4-hydroxy-2-pyranone derivatives and their difluoridoborate complexes as a novel class of HIV-1 integrase Inhibitors Original Research Article
92
Discovery of 3-Amino-4-Chlorophenyl P1 as a novel and potent benzamidine mimic via solid-phase synthesis of an isoxazoline library
93
Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors
94
Discovery of 3-aryl-3-methyl-1H-quinoline-2,4-diones as a new class of selective 5-HT6 receptor antagonists
95
Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes
96
Discovery of 3-hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles as potent MEK1 inhibitors
97
Discovery of 3-OH-3-methylpipecolic hydroxamates: Potent orally active inhibitors of aggrecanase and MMP-13
98
Discovery of 4-(dimethylamino)quinazolines as potent and selective antagonists for the melanin-concentrating hormone receptor 1
99
Discovery of 4,5-Diphenyl-1,2,4-triazole Derivatives as a Novel Class of Selective Antagonists for the Human V1A Receptor Original Research Article
100
Discovery of 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4′-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2′-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors
101
Discovery of 4′-[(Imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/Angiotensin II receptor antagonists
102
Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR
103
Discovery of 4-aryl-2-oxo-2H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay
104
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure–activity relationships of the 7- and 5-, 6-, 8-positions
105
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: Modifications of the 2- and 3-positions
106
Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11β-HSD1: Novel therapeutic agents for the treatment of metabolic syndrome
107
Discovery of 4-substituted-8-(2-hydroxy-2-phenyl-cyclohexyl)-2,8-diaza-spiro[4.5]decan-1-one as a novel class of highly selective GlyT1 inhibitors with improved metabolic stability
108
Discovery of 5-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-7-phenyl-(E)-2,3,6,7-tetrahydro-1,4-thiazepines as a new series of apoptosis inducers using a cell- and caspase-based HTS assay
109
Discovery of 5-HT6 receptor ligands based on virtual HTS
110
Discovery of 5-Hydroxyalkyl-4-phenylpyridines as a New Class of Glucagon Receptor Antagonists
111
Discovery of 60Ge and 64Se
112
Discovery of 6-ethyl-2,4-diaminopyrimidine-based small molecule renin inhibitors
113
Discovery of 7α-substituted dihydrotestosterones as androgen receptor pure antagonists and their structure–activity relationships Original Research Article
114
Discovery of a 7 second anomalous X-ray pulsar in the distant Milky Way
115
Discovery of a Binary Active Galactic Nucleus in the Ultraluminous Infrared Galaxy NGC 6240 Using Chandra
116
Discovery of a binary Centaur
117
Discovery of a c.370 Ma granitic gneiss clast from the Hwanggangri pebble-bearing phyllite in the Okcheon metamorphic belt, Korea
118
Discovery of a coherent 87.65-minute oscillation of the suspected cataclysmic variable NSV 2872 (Aur 2)
119
Discovery of a dihydropyrimidine series of molecules that selectively mimic the biological actions of calcitonin
120
Discovery of a dismembered metamorphic sole in the Saga ophiolitic mélange, South Tibet: Assessing an Early Cretaceous disruption of the Neo-Tethyan supra-subduction zone and consequences on basin closing
121
Discovery of a dopamine D4 selective PET ligand candidate taking advantage of a click chemistry based REM linker
122
Discovery of a double impact crater in Libya: the astrobleme of Arkenu
123
Discovery of a dust cloud next to (sigma)Orionis
124
Discovery of a faint R-band drop-out: A strongly reddened lensed star forming galaxy at z = 1.68
125
Discovery of a giant deep-sea valley in the Indian Ocean, off eastern Africa: The Tanzania channel
126
Discovery of a helium-core white dwarf progenitor
127
Discovery of a hidden BIF deposit in Anhui province, China by integrated geological and geophysical investigations
128
Discovery of a highly orally bioavailable c-5-[6-(4-Methanesulfonyloxyphenyl)hexyl]-2-methyl-1,3-dioxane-r-2-carboxylic acid as a potent hypoglycemic and hypolipidemic agent
129
Discovery of a highly potent series of oxazole-based phosphodiesterase 4 inhibitors
130
Discovery of a highly potent, functionally-selective muscarinic M1 agonist,WAY-132983 using rational drug design and receptor modelling
131
Discovery of a huge sector collapse at the Nisyros volcano, Greece, by on-land and offshore geological-structural data
132
Discovery of a Late Ordovician Foliomena fauna in the Tarim desert, Northwest China
133
Discovery of a Low-Mass Bipolar Molecular Outflow from L1014-IRS with the Submillimeter Array
134
Discovery of a luminous water megamaser in the FR II radiogalaxy 3C 403
135
Discovery of a magnetic field in the Slowly Pulsating B star Cassiopeiae
136
Discovery of a Magnetic Ionic Liquid [bmim]FeCl4
137
Discovery of a mass grave of Napoleonic period in Lithuania (1812, Vilnius)
138
Discovery of a Mesolithic burial near the painted rock-shelter of Ban Tha Si (Lampang province, Northern Thailand): Implications for regional mortuary practices
139
Discovery of a missing disease spreader
140
Discovery of a muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors among 2-[(1S,3S)-3-sulfonylaminocyclopentyl]phenylacetamide derivatives Original Research Article
141
Discovery of a N′-hydroxyphenylformamidine derivative HET0016 as a potent and selective 20-HETE synthase inhibitor
142
Discovery of a Nearby Halo White Dwarf with Proper Motion (mu) = 2n55 yr^-1
143
Discovery of a Neoproterozoic basin in the Prydz belt in East Antarctica and its implications for Gondwana assembly and ultrahigh temperature metamorphism
144
Discovery of a new 2.3 s isomer in neutron-rich 174Tm
145
Discovery of a new catalytically active and selective zeolite (ITQ-30) by high-throughput synthesis techniques
146
Discovery of a new chemical lead for a matrix metalloproteinase inhibitor Original Research Article
147
Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies
148
Discovery of a new class of p38 kinase inhibitors
149
Discovery of a new class of potent, selective, and orally active prostaglandin D2 receptor antagonists Original Research Article
150
Discovery of A New Class of Pulsating Stars: Gravity-Mode Pulsators among Subdwarf B Stars
151
Discovery of a new cyclooxygenase-2 lead compound through 3-D database searching and combinatorial chemistry
152
Discovery of a new element ‘nipponium’: re-evaluation of pioneering works of Masataka Ogawa and his son Eijiro Ogawa
153
Discovery of a new Fe-type nitrile hydratase efficiently hydrating aliphatic and aromatic nitriles by genome mining
154
Discovery of a new hydrothermal vent based on an underwater, high-resolution geophysical survey
155
Discovery of a new insecticide lead by optimizing a target-diverse scaffold: Tetrazolinone derivatives Original Research Article
156
Discovery of a New Role of Human Resistin in Hepatocyte Low-Density Lipoprotein Receptor Suppression Mediated in Part by Proprotein Convertase Subtilisin/Kexin Type 9
157
Discovery of a new species of Lonchodryinus from Madagascar (Hymenoptera, Dryinidae)
158
Discovery of a nonpeptidic small molecule antagonist of the human platelet thrombin receptor (PAR-1)
159
Discovery of a novel abl tyrosine kinase inhibitor that selectively induces apoptosis of bcr-abl-positive leukemic cells
160
Discovery of a novel and potent series of dianilinopyrimidineurea and urea isostere inhibitors of VEGFR2 tyrosine kinase
161
Discovery of a novel and potent series of thieno[3,2-b]pyridine-based inhibitors of c-Met and VEGFR2 tyrosine kinases
162
Discovery of a novel antimicrobial peptide using membrane binding-based approach
163
Discovery of a novel benzyloxyisoquinoline derivative with potent anti-Helicobacter pylori activity
164
Discovery of a novel bicycloproline P2 bearing peptidyl α-ketoamide LY514962 as HCV protease inhibitor
165
Discovery of a novel CCR3 selective antagonist
166
Discovery of a novel class of 1,3-dioxane-2-carboxylic acid derivatives as subtype-selective peroxisome proliferator-activated receptor α (PPARα) agonists
167
Discovery of a novel class of 2-ureido thiophene carboxamide checkpoint kinase inhibitors
168
Discovery of a novel class of benzazepinone Nav1.7 blockers: Potential treatments for neuropathic pain
169
DISCOVERY OF A NOVEL CLASS OF BK CHANNEL OPENERS: ENANTIOSPECIFIC SYNTHESIS AND BK CHANNEL OPENING ACTIVITY OF 3-(5-CHLORO-2-HYDROXYPHENYL)-1,3-DIHYDRO-3-HYDROXY-6-(TRIFLUOROMETHYL)-2H-INDOL-2-ONE
170
Discovery of a novel class of PPARδ partial agonists
171
Discovery of a novel class of selective human CB1 inverse agonists
172
Discovery of a Novel Family of CDK Inhibitors with the Program LIDAEUS: Structural Basis for Ligand-Induced Disordering of the
173
Discovery of a novel indole series of EP1 receptor antagonists by scaffold hopping
174
Discovery of a novel lead structure for anti-malarials Original Research Article
175
Discovery of a novel one-step RuO4-catalysed tandem oxidative polycyclization/double spiroketalization process. Access to a new type of polyether bis-spiroketal compound displaying antitumour activity
176
Discovery of a novel potent Na+/Ca2+ exchanger inhibitor: design, synthesis and structure–activity relationships of 3,4-dihydro-2(1H)-quinazolinone derivatives
177
Discovery of a novel series of 6-azauracil-based thyroid hormone receptor ligands: potent, TRβ subtype-selective thyromimetics
178
Discovery of a novel series of DHODH inhibitors by a docking procedure and QSAR refinement
179
Discovery of a novel series of inhibitors of human cytomegalovirus primase
180
Discovery of a novel series of nonsteroidal androgen receptor modulators: 5- or 6-oxachrysen-2-ones
181
Discovery of a novel series of Notch-sparing γ-secretase inhibitors
182
Discovery of a novel series of selective MMP inhibitors: Identification of the γ-sulfone-thiols
183
Discovery of a novel small molecule binding site of human survivin
184
Discovery of a novel small molecule, 1-ethoxy-3-(3,4-methylenedioxyphenyl)-2-propanol, that induces apoptosis in A549 human lung cancer cells Original Research Article
185
Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase
186
Discovery of a novel tetrahydroacridine acetylcholinesterase inhibitor through an indexed combinatorial library Original Research Article
187
Discovery of a novel, potent and orally active series of γ-lactams as selective NK1 antagonists
188
Discovery of a novel, potent and selective human β3-adrenergic receptor agonist
189
Discovery of a nuclease-resistant, non-natural dinucleotide that inhibits HIV-1 integrase
190
Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry
191
Discovery of a potent and selective agonist of the prostaglandin EP4 receptor
192
Discovery of a potent and selective Aurora kinase inhibitor
193
Discovery of a potent and selective c-Kit inhibitor for the treatment of inflammatory diseases
194
Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile
195
Discovery of a potent and selective series of pyrazole bacterial methionyl-tRNA synthetase inhibitors
196
Discovery of a potent and selective αvβ3 integrin antagonist with strong inhibitory activity against neointima formation in rat balloon injury model
197
Discovery of a potent CDK2 inhibitor with a novel binding mode, using virtual screening and initial, structure-guided lead scoping
198
Discovery of a potent phenolic N1-benzylidene–pyridinecarboxamidrazone selective against Gram-positive bacteria
199
Discovery of a potent, non-triketone type inhibitor of 4-hydroxyphenylpyruvate dioxygenase
200
Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine
201
Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI)
202
Discovery of a prehistoric site at Sao Din (Nanoi, Nan province, Northern Thailand): Stone tools and new geological insights
203
Discovery of a Proneurogenic, Neuroprotective Chemical
204
Discovery of a recent, natural whale fall on the continental slope off Anvers Island, western Antarctic Peninsula
205
Discovery of a recurrent lava lake on Saunders Island (South Sandwich Islands) using AVHRR imagery
206
Discovery of a reductase-producing strain recombinant E. coli CCZU-A13 using colorimetric screening and its whole cell-catalyzed biosynthesis of ethyl (R)-4-chloro-3-hydroxybutanoate
207
Discovery of a Secreted Tumor Suppressor Provides a Promising Therapeutic Strategy for Follicular Lymphoma
208
Discovery of a series of (4,5-Dihydroimidazol-2-yl)-biphenylamine 5-HT7 agonists
209
Discovery of a series of acrylic acids and their derivatives as chemical leads for selective EP3 receptor antagonists Original Research Article
210
Discovery of a series of aminopiperidines as novel iNOS inhibitors
211
Discovery of a series of pyrrolidine-based endothelin receptor antagonists with enhanced ETA receptor selectivity Original Research Article
212
Discovery of a Small Molecule that Inhibits the Interaction of Anthrax Edema Factor with Its Cellular Activator, Calmodulin Original Research Article
213
Discovery of a strong magnetic field in the rapidly rotating B2Vn star HR7355
214
Discovery of a substituted 8-arylquinoline series of PDE4 inhibitors: Structure–activity relationship, optimization, and identification of a highly potent, well tolerated, PDE4 inhibitor
215
Discovery of a Substrate Selectivity Switch in Tyrosine Ammonia-Lyase, a Member of the Aromatic Amino Acid Lyase Family Original Research Article
216
Discovery of a sulfated tetrapeptide that binds to vascular endothelial growth factor
217
Discovery of a Thermophilic Protein Complex Stabilized by Topologically Interlinked Chains
218
Discovery of a Tight Brown Dwarf Companion to the Low-Mass Star LHS 2397a
219
Discovery of a Two-Component Monooxygenase SnoaW/SnoaL2 Involved in Nogalamycin Biosynthesis Original Research Article
220
Discovery of a very extended X-ray halo around a quiescent spiral galaxy – The “missing link” of galaxy formation
221
Discovery of a Wide, Low-Mass Binary System in Upper Scorpius
222
Discovery of a young asteroid cluster associated with P/2012 F5 (Gibbs)
223
Discovery of a z = 6.17 galaxy from CFHT and VLT observations
224
Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection
225
Discovery of actinium, thorium, protactinium, and uranium isotopes
226
Discovery of active hydrothermal venting in Lake Taupo, New Zealand
227
Discovery of active site of vinblastine as application of nanotechnology in medicine
228
Discovery of active site of vinblastine as application of nanotechnology in medicine
229
Discovery of adamantane ethers as inhibitors of 11β-HSD-1: Synthesis and biological evaluation
230
Discovery of ADC absorption in the LMXB XB 1323-619 with XMM-Newton Original Research Article
231
Discovery of additional lead-rich stars
232
Discovery of agglutinated benthic foraminifera in Devonian black shales and their relevance for the redox state of ancient seas
233
Discovery of AICAR Tfase inhibitors that disrupt requisite enzyme dimerization
234
Discovery of alcohol dehydrogenase from mushrooms and application to alcoholic beverages
235
Discovery of amide and heteroaryl isosteres as carbamate replacements in a series of orally active γ-secretase inhibitors
236
Discovery of amido-benzisoxazoles as potent c-Kit inhibitors
237
Discovery of amino acid amides as new substrates for α-amino-ɛ-caprolactam racemase from Achromobacter obae
238
Discovery of amino-acetonitrile derivatives, a new class of synthetic anthelmintic compounds
239
Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling Original Research Article
240
Discovery of an adakite-like pluton near Dongqiyishan (Beishan, NW China) — Its age and tectonic significance
241
Discovery of an alkaline orthogneiss in the eclogite-bearing Cellier Unit (Champtoceaux Complex, Armorican Massif): a new witness of the Ordovician rifting
242
DISCOVERY OF AN ALTERNATIVELY SPLICED FORM OF BRAIN NATRIURETIC PEPTIDE: CHARACTERIZATION AND FUNCTION
243
Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones
244
Discovery of an archaic Homo sapiens skullcap in Northeast Mongolia
245
Discovery of an Aurora kinase inhibitor through site-specific dynamic combinatorial chemistry
246
Discovery of an Autunian macroflora and lithostratigraphic re-investigation on the western border of the Lodève Permian basin (Mont Sénégra, Hérault, France). Paleoenvironmental implications
247
Discovery of an endophytic alga in Ginkgo biloba
248
Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency and selectivity
249
Discovery of an ice cave in the Yatude Valley, Langhovde, Dronning Maud Land, East Antarctica
250
Discovery of an imidazopyridine-containing 1,4-benzodiazepine nonpeptide vitronectin receptor (αvβ3) antagonist with efficacy in a restenosis model
251
Discovery of an in situ carbocationic system using trityl chloride as a homogeneous organocatalyst for the solvent-free condensation of β-naphthol with aldehydes and amides/thioamides/alkyl carbamates in neutral media
252
Discovery of an Iron-Regulated Citrate Synthase in Staphylococcus aureus Original Research Article
253
Discovery of an M4 Spectroscopic Binary in Upper Scorpius: A Calibration Point for Young Low-Mass Evolutionary Models
254
Discovery of an N-(2-aminopyridin-4-ylmethyl)nicotinamide derivative: a potent and orally bioavailable NCX inhibitor Original Research Article
255
Discovery of an Optically Faint Quasar at z = 5.70 and Implications for the Faint Endof the Quasar Luminosity Function
256
Discovery of an orally bioavailable alkyl oxadiazole β3 adrenergic receptor agonist
257
Discovery of an orally efficaceous 4-phenoxypyrrolidine-based BACE-1 inhibitor
258
Discovery of an outcropping Mass Transport Deposit (MTD) in the Palaeogene subalpine synclines of southeastern France: Implications on flexural sub-basin deformation
259
Discovery of an Ultracool Subdwarf: LSR 1425+7102, the First Star with Spectral Type sdM8.0
260
Discovery of an Upper Miocene Vertebrate fauna near Tizi N’Tadderht, Skoura, Ouarzazate Basin (Central High Atlas, Morocco)
261
Discovery of Antagonist Peptides against Bacterial Helicase-Primase Interaction in B. stearothermophilus by Reverse Yeast Three-Hybrid Original Research Article
262
Discovery of Antagonists of PqsR, a Key Player in 2-Alkyl-4-quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa Original Research Article
263
Discovery of anticonvulsant activity of abietic acid through application of linear discriminant analysis
264
Discovery of anti-influenza A virus activity of a corynanthe-type indole alkaloid, hirsutine, in vitro and the structure-activity relationship of natural and synthetic analogs
265
Discovery of antirhinoviral leads by screening a combinatorial library of ureas prepared using covalent scavengers
266
Discovery of Archaean crust within the Akitkan orogenic belt of the Siberian craton: New insight into its architecture and history
267
Discovery of azetidinone acids as conformationally-constrained dual PPARα/γ agonists
268
Discovery of Baeyer–Villiger monooxygenases from photosynthetic eukaryotes
269
Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90
270
Discovery of benzo[g]indol-3-carboxylates as potent inhibitors of microsomal prostaglandin E2 synthase-1 Original Research Article
271
Discovery of benzoylpiperazines as a novel class of potent and selective GlyT1 inhibitors
272
Discovery of betamethasone 17α-carbamates as dissociated glucocorticoid receptor modulators in the rat Original Research Article
273
Discovery of Bioactive Small-Molecule Inhibitor of Poly ADP-Ribose Polymerase: Implications for Energy-Deficient Cells Original Research Article
274
Discovery of bitriazolyl compounds as novel antiviral candidates for combating the tobacco mosaic virus
275
Discovery of brain penetrant, soluble, pyrazole amide EP1 receptor antagonists
276
Discovery of cancer biomarkers through the use of mouse models
277
Discovery of candidate phospholipid biomarkers in human lipoproteins with coronary artery disease by flow field-flow fractionation and nanoflow liquid chromatography–tandem mass spectrometry
278
Discovery of carboxypeptidase Y as a catalyst for the incorporation of sterically demanding α-fluoroalkyl amino acids into peptides
279
Discovery of cesium, lanthanum, praseodymium and promethium isotopes
280
Discovery of CH4-rich high-pressure fluid inclusions hosted in analcime from Dongying depression, China
281
Discovery of chromium, manganese, nickel, and copper isotopes
282
Discovery of classes among deep level centers in gallium arsenide
283
Discovery of co2 ice and leading–trailing spectral asymmetry on the uranian satellite ariel
284
Discovery of conformationally rigid 3-azabicyclo[3.1.0]hexane-derived dipeptidyl peptidase-IV inhibitors
285
Discovery of Conserved and Novel MicroRNAs in Galdieria sulphuraria
286
Discovery of Conserved Sequence Patterns Using a Stochastic Dictionary Model
287
Discovery of coumarin as the predominant allelochemical in Gliricidia sepium
288
Discovery of CP-199,330 and CP-199,331: Two potent and orally efficacious cysteinyl LT1 receptor antagonists devoid of liver toxicity
289
Discovery of cubic diamond and sp2 carbon micro-particles in “Chelyabinsk” meteorite by Raman micro-mapping
290
Discovery of cyclopentane- and cyclohexane-trans-1,3-diamines as potent melanin-concentrating hormone receptor 1 antagonists
291
Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists
292
Discovery of diaminobutane derivatives as Ca2+-permeable AMPA receptor antagonists Original Research Article
293
Discovery of dihydroquinoxalinone acetamides containing bicyclic amines as potent Bradykinin B1 receptor antagonists
294
Discovery of diphenylcarbamate derivatives as highly potent and selective IP receptor agonists: Orally active prostacyclin mimetics. Part 3
295
Discovery of dipolar-glassy state in a newly found solid–solution system of C5NH6(BF4)1−x(PF6)x
296
Discovery of direct inhibitor of KRAS oncogenic protein by natural products: a combination of pharmacophore search, molecular docking, and molecular dynamic studies
297
Discovery of distyly in Narcissus (Amaryllidaceae)
298
Discovery of dividing neurons in human brains excites researchers
299
Discovery of doubly-magic 48Ni at GANIL Original Research Article
300
Discovery of Drug-Resistant and Drug-Sensitizing Mutations in the Oncogenic PI3K Isoform p110α
301
Discovery of Dual Inhibitors of the Immune Cell PI3Ks p110δ and p110γ: a Prototype for New Anti-inflammatory Drugs Original Research Article
302
Discovery of dysprosium, holmium, erbium, thulium, and ytterbium isotopes
303
Discovery of Early Optical Emission from GRB 021211
304
Discovery of Early Paleozoic eclogite from the East Kunlun, Western China and its tectonic significance
305
Discovery of effective solvents for platelet-type graphite nanofibers Original Research Article
306
Discovery of Erysiphe platani anamorph on Platanus × hispanica from Brazil
307
Discovery of factors influencing citation impact based on a soft fuzzy rough set model
308
Discovery of factors influencing patent value based on machine learning in patents in the field of nanotechnology
309
Discovery of feature-based hot spots using supervised clustering
310
Discovery of FK453, a novel non-xanthine adenosine A1 receptor antagonist
311
Discovery of FR115092 : A novel antinephritic agent
312
Discovery of FR166124, a novel water-soluble pyrazolo-[1,5-α]pyridine adenosine A1 receptor antagonist
313
Discovery of functional protein groups by clustering community links and integration of ontological knowledge
314
Discovery of fuzzy quantitative sequential patterns with multiple minimum supports and adjustable membership functions
315
Discovery of galectin ligands in fully randomized combinatorial one-bead-one-compound (glyco)peptide libraries
316
Discovery of gallium, germanium, lutetium, and hafnium isotopes
317
Discovery of GS-9131: Design, synthesis and optimization of amidate prodrugs of the novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148 Original Research Article
318
Discovery of Habritys brevicornis (Ratzeburg, 1844) (Hymenoptera: Pteromalidae) in the Middle-East
319
Discovery of halogenated eurypamide B analogues as inhibitors of lipid droplet accumulation in macrophages
320
Discovery of hazardous foreign bodies observed during anesthetic practice
321
Discovery of Helicobacter pylori shikimate kinase inhibitors: Bioassay and molecular modeling Original Research Article
322
Discovery of heteroaryl sulfonamides as new EP1 receptor selective antagonists Original Research Article
323
Discovery of heterobicyclic templates for novel metabotropic glutamate receptor subtype 5 antagonists
324
Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach
325
Discovery of hexacoordinate hypervalent carbon compounds: Density functional study
326
Discovery of Hg–Cu-bearing metal-sulfide assemblages in a primitive H-3 chondrite: Towards a new insight in early solar system processes
327
Discovery of hidden correlations in a local transaction database based on differences of correlations
328
Discovery of high utility itemsets from on-shelf time periods of products
329
Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) δ agonists
330
Discovery of highly potent Src SH2 binders: Structure–activity studies and X-ray structures
331
Discovery of highly potent, selective, orally bioavailable, metabotropic glutamate subtype 5 (mGlu5) receptor antagonists devoid of cytochrome P450 1A2 inhibitory activity
332
Discovery of highly selective EP4 receptor agonists that stimulate new bone formation and restore bone mass in ovariectomized rats
333
Discovery of high-pressure granulite-facies metamorphism in northern Vietnam: Constraints on the Permo-Triassic Indochinese continental collision tectonics
334
Discovery of historical Tainan: a digital approach
335
Discovery of Holocene millennial climate cycles in the Asian continental interior: Has the sun been governing the continental climate?
336
Discovery of human CCR5 antagonists containing hydantoins for the treatment of HIV-1 infection
337
Discovery of human zinc deficiency: 50 years later
338
Discovery of human zinc deficiency: impact on human health
339
Discovery of hydrometeorological patterns
340
Discovery of hydrothermal sulfide mineralization from southern Kermadec arc volcanoes (SW Pacific)
341
Discovery of hydroxamic acid analogs as dual inhibitors of phosphodiesterase-1 and -5
342
Discovery of imidazo[1,2-c]pyrimidin-5(6H)-one heterosubstituted nucleoside analogues with potent activity against human hepatitis B virus in
343
Discovery of imidazole carboxamides as potent and selective CCK1R agonists
344
Discovery of imidazole glycerol phosphate dehydratase inhibitors through 3-D database searching
345
Discovery of imidazole vinyl pyrimidines as a novel class of kinase inhibitors which inhibit Tie-2 and are orally bioavailable
346
Discovery of imidazolidine-2,4-dione-linked HIV protease inhibitors with activity against lopinavir-resistant mutant HIV Original Research Article
347
Discovery of Iminobenzimidazole Derivatives as Novel Cytotoxic Agents
348
Discovery of immune molecules and their crucial functions in shrimp immunity
349
Discovery of Improved EGF Agonists Using a Novel In Vitro Screening Platform
350
Discovery of impurities existing state in carbide slag by chemical dissociation
351
Discovery of indenopyrazoles as EGFR and VEGFR-2 tyrosine kinase inhibitors by in silico high-throughput screening
352
Discovery of Independence: South Asia at 63
353
Discovery of indole-containing tetracycles as a new scaffold for androgen receptor ligands
354
Discovery of inhibitors of brassinin oxidase based on the scaffolds of the phytoalexins brassilexin and wasalexin Original Research Article
355
Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target
356
Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design
357
Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis
358
Discovery of Inhibitors that Elucidate the Role of UCH-L1 Activity in the H1299 Lung Cancer Cell Line Original Research Article
359
Discovery of insect parasitism and subsequent development of parasitoid research in Japan
360
Discovery of invisible extra fronts in single-component frontal analysis in liquid chromatography
361
Discovery of iridium and other element anomalies near the 1908 Tunguska explosion site
362
Discovery of IRL 3461: a novel and potent endothelin antagonist with balanced ETA/ETB affinity
363
Discovery of iron-K absorption lines from the transient jets GRS 1915+105 and GRO J1655-40 Original Research Article
364
Discovery of isotopes of elements with
365
Discovery of isotopes of the transuranium elements with 93≤Z≤98
366
Discovery of isotopes with
367
Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials
368
Discovery of Jadeite-Jade in Guatemala Confirmed by Non-Destructive Raman Microscopy
369
Discovery of jarosite within the Mawrth Vallis region of Mars: Implications for the geologic history of the region
370
Discovery of jet quenching and beyond Original Research Article
371
Discovery of jet quenching at RHIC and the opacity of the produced gluon plasma Original Research Article
372
Discovery of Kibdelomycin, A Potent New Class of Bacterial Type II Topoisomerase Inhibitor by Chemical-Genetic Profiling in Staphylococcus aureus Original Research Article
373
Discovery of Kilohertz Quasi-periodic Oscillations and Shifted Frequency Correlations in the Accreting Millisecond Pulsar XTE J1807294
374
Discovery of L-740,515, a potent thienopyridine cysLT1 receptor (LTD4 receptor) antagonist
375
Discovery of L-755,507: A subnanomolar human β3 adrenergic receptor agonist
376
Discovery of L-791,943: A potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor
377
Discovery of Latest Devonian/Earliest Mississippian microfossils in San Salvador Patlanoaya (Puebla, Mexico); biogeographic and geodynamic consequences
378
Discovery of LB30057, a benzamidrazone-based selective oral thrombin inhibitor
379
Discovery of long-acting N-(cyanomethyl)-N-alkyl-l-prolinamide inhibitors of dipeptidyl peptidase IV Original Research Article
380
Discovery of low mucus adhesion surfaces
381
Discovery of low nanomolar non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)
382
Discovery of magnetic field variations with the 12.1-minute pulsation period of the roAp star (gamma) Equulei
383
Discovery of male of Proconura persica Delvare (Hymenoptera: Chalcididae), recently described from Iran
384
Discovery of mass spectral characteristics and automatic identification of wax esters from gas chromatography mass spectrometry data
385
Discovery of maximum length frequent itemsets
386
Discovery of melanin-concentrating hormone receptor R1 antagonists using high-throughput synthesis Original Research Article
387
Discovery of Messinian canyons and new seismic stratigraphic model, offshore Provence (SE France): Implications for the hydrographic network reconstruction
388
Discovery of metastable tetragonal disordered phase upon phase transitions in the equiatomic nanostructured FePd alloy Original Research Article
389
Discovery of micromolar PDE IV inhibitors that exhibit much reduced affinity for the [3H]rolipram binding site: 3-norbornyloxy-4-methoxyphenylmethylene oxindoles
390
Discovery of microscopic evidence for shock metamorphism at the Serpent Mound structure, south-central Ohio: confirmation of an origin by impact
391
Discovery of Middle Jurassic (Bajocian) Radiolaria from the sedimentary cover of the Vedi ophiolite (Lesser Caucasus, Armenia)
392
Discovery of Miocene adakitic dacite from the Eastern Pontides Belt (NE Turkey) and a revised geodynamic model for the late Cenozoic evolution of the Eastern Mediterranean region
393
Discovery of MK-0476, a potent and orally active leukotriene D4 receptor antagonist devoid of peroxisomal enxyme induction
394
Discovery of N-(2-aryl-cyclohexyl) substituted spiropiperidines as a novel class of GlyT1 inhibitors
395
Discovery of N-(2-hydroxy-2-aryl-cyclohexyl) substituted spiropiperidines as GlyT1 antagonists with improved pharmacological profile
396
Discovery of N-[(3R,5R)-1-azabicyclo[3.2.1]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide as an agonist of the α7 nicotinic acetylcholine receptor: In vitro and in vivo activity
397
Discovery of narrow X-ray absorption features from the low-mass X-ray binary X 1254-690 with XMM-Newton
398
Discovery of neurosteroid glucuronides in mouse brain Original Research Article
399
Discovery of new angiotensin converting enzyme (ACE) inhibitors from medicinal plants to treat hypertension using an in vitro assay
400
Discovery of new binding elements in DPP-4 inhibition and their applications in novel DPP-4 inhibitor design
401
Discovery of New Bioactive Secondary Metabolites from Psychrophilic Microorganisms — Mini Review
402
Discovery of new C3aR ligands. Part 1: Arginine derivatives
403
Discovery of new C3aR ligands. Part 2: Amino-piperidine derivatives
404
Discovery of new catalytic materials for the water–gas shift reaction by high-throughput experimentation Original Research Article
405
Discovery of new chemical leads for prostaglandin D2 receptor antagonists
406
Discovery of new chemical leads for selective EP1 receptor antagonists Original Research Article
407
Discovery of new diphenyloxazole derivatives containing a pyrrolidine ring: Orally active prostacyclin mimetics. Part 2
408
Discovery of New Drugs Against Tuberculosis: History Guides
409
Discovery of new fuel-lean NO reduction catalyst leads using combinatorial methodologies
410
Discovery of new Gram-negative antivirulence drugs: Structure and properties of novel E. coli WaaC inhibitors
411
Discovery of new hydrothermal vent sites in Bransfield Strait, Antarctica
412
Discovery of new hydrothermal vent sites in Bransfield Strait, Antarctica
413
Discovery of new inhibitors of aldose reductase from molecular docking and database screening Original Research Article
414
Discovery of new Milky Way star cluster candidates in the 2MASS Point Source Catalog. II. Physical properties of the star cluster CC 01
415
Discovery of new MurF inhibitors via pharmacophore modeling and QSAR analysis followed by in-silico screening Original Research Article
416
Discovery of new paraffin isomerization catalysts based on SO42−/ZrO2 and WOx/ZrO2 applying combinatorial techniques
417
Discovery of new peptide-Based catalysts for the direct asymmetric aldol reaction
418
Discovery of new phase and analysis of phase relationships in BaBiO3 with thermal analyses
419
Discovery of new pyridoacridine alkaloids from Lissoclinum cf. badium that inhibit the ubiquitin ligase activity of Hdm2 and stabilize p53 Original Research Article
420
Discovery of new small molecules that influence neuroblast cell migration from the subventricular zone
421
Discovery of N-Hydroxy-2-(2-oxo-3-pyrrolidinyl)acetamides as potent and selective inhibitors of tumor necrosis factor-α converting enzyme (TACE)
422
Discovery of non-A, non-B hepatitis and identification of its etiology
423
Discovery of non-carbohydrate inhibitors of aminoglycoside-modifying enzymes Original Research Article
424
Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site
425
Discovery of non-peptidic P2–P3 butanediamide renin inhibitors with high oral efficacy Original Research Article
426
Discovery of nonsteroidal glucocorticoid receptor ligands based on 6-indole-1,2,3,4-tetrahydroquinolines
427
Discovery of non-steroidal mifepristone mimetics: Pyrazoline-based PR antagonists
428
Discovery of non-Zwitterionic GABAA receptor full agonists and a superagonist
429
Discovery of novel 1,2,3,4-tetrahydroisoquinolines and 3,4-dihydroisoquinoline-1(2H)-ones as potent and selective inhibitors of KDR: Synthesis, SAR, and pharmacokinetic properties
430
Discovery of Novel 1,2,3-Triazole Analogues as Anti-Tuberculosis agents Using 3D QSAR, Molecular Docking, and In Silico ADMET Screening
431
Discovery of novel 1-arylmethyl pyrrolidin-2-yl ethanol amines as calcium-sensing receptor antagonists
432
Discovery of novel 2-(aminoheteroaryl)-thiazole-5-carboxamides as potent and orally active Src-family kinase p56Lck inhibitors
433
Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties
434
Discovery of novel 4-amino-6-arylaminopyrimidine-5-carbaldehyde oximes as dual inhibitors of EGFR and ErbB-2 protein tyrosine kinases
435
Discovery of novel 8-azoniabicyclo[3.2.1]octane carbamates as muscarinic acetylcholine receptor antagonists
436
Discovery of novel and orally active NR2B-selective N-methyl-d-aspartate (NMDA) antagonists, pyridinol derivatives with reduced HERG binding affinity
437
Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors
438
Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1
439
Discovery of novel and selective tertiary alcohol containing inhibitors of the norepinephrine transporter
440
Discovery of novel aspartyl ketone dipeptides as potent and selective caspase-3 inhibitors
441
Discovery of novel benzimidazolones as potent non-nucleoside reverse transcriptase inhibitors active against wild-type and mutant HIV-1 strains
442
Discovery of novel benzothiazolesulfonamides as potent inhibitors of HIV-1 protease Original Research Article
443
Discovery of novel biaryl heterocyclic EP1 receptor antagonists
444
Discovery of novel conformationally constrained tropane-based biaryl and arylacetylene ligands as potent and selective norepinephrine transporter inhibitors and potential antidepressants
445
Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1β synthesis
446
Discovery of novel dialkyl substituted thiophene inhibitors of HCV by in silico screening of the NS5B RdRp
447
Discovery of novel dual functional agent as PPARγ agonist and 11β-HSD1 inhibitor for the treatment of diabetes Original Research Article
448
Discovery of novel FMS kinase inhibitors as anti-inflammatory agents
449
Discovery of Novel Glucagon Receptor Antagonists Using Combined Pharmacophore Modeling and Docking
450
Discovery of novel heteroaryl-substituted chalcones as inhibitors of TNF-α-induced VCAM-1 expression
451
Discovery of novel heterocyclic factor VIIa inhibitors
452
Discovery of novel homogeneous rare earth catalysts by IR-thermography: epoxide opening with alcohols and Baeyer–Villiger oxidations with hydrogen peroxide Original Research Article
453
Discovery of novel hydantoins as selective non-hydroxamate inhibitors of tumor necrosis factor-α converting enzyme (TACE)
454
Discovery of novel hydroxamates as highly potent tumor necrosis factor-α converting enzyme inhibitors. Part II: Optimization of the S3′ pocket
455
Discovery of novel hydroxy pyrazole based factor IXa inhibitor
456
Discovery of novel hydroxy-thiazoles as HIF-α prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation
457
Discovery of novel indazole-linked triazoles as antifungal agents
458
Discovery of novel inhibitors of 11β-hydroxysteroid dehydrogenase type 1 by docking and pharmacophore modeling
459
Discovery of novel inhibitors of ghrelin O-acyltransferase enzyme: an in-silico approach
460
Discovery of novel isatin-based thiosemicarbazones: synthesis, antibacterial, antifungal, and antimycobacterial screening
461
Discovery of novel isothiazole inhibitors of the TrkA kinase: Structure–activity relationship, computer modeling, optimization, and identification of highly potent antagonists
462
Discovery of novel isoxazolines as anti-tuberculosis agents
463
Discovery of novel low molecular weight inhibitors of IMPDH via virtual needle screening
464
Discovery of Novel Mastitis-Related SNP and RNA Splicing on HSF1 Gene in Chinese Holstein Cattle
465
Discovery of novel modulators of metabotropic glutamate receptor subtype-5 Original Research Article
466
Discovery of novel neuronal voltage-Dependent calcium channel blockers based on emopamil left hand as a bioactive template
467
Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors
468
Discovery of novel nonpeptide tricyclic inhibitors of ras farnesyl protein transferase Original Research Article
469
Discovery of novel non-peptidic ketopiperazine-based renin inhibitors Original Research Article
470
Discovery of novel nonsteroidal glucocorticoid receptor modulators
471
Discovery of novel orally active ureido NPY Y5 receptor antagonists
472
Discovery of Novel Peptidomimetics for Brain-Derived Neurotrophic Factor using Phage Display Technology
473
Discovery of Novel Phosphonic Acid Derivatives as New Chemical Leads for Inhibitors of TNF-α production Original Research Article
474
Discovery of novel phosphorus-containing steroids as selective glucocorticoid receptor antagonist
475
Discovery of novel potent and selective dipeptide hepatitis C virus NS3/4A serine protease inhibitors
476
Discovery of novel PRL-3 inhibitors based on the structure-based virtual screening
477
Discovery of novel prostaglandin analogs of PGE2 as potent and selective EP2 and EP4 receptor agonists
478
Discovery of novel PTP1b inhibitors
479
Discovery of novel purine derivatives with potent and selective inhibitory activity against c-Src tyrosine kinase Original Research Article
480
Discovery of novel series of benzoic acid derivatives containing biphenyl ether moiety as potent and selective human β3-adrenergic receptor agonists: Part IV
481
Discovery of novel sesquiterpenoids from a gorgonian Menella sp.
482
Discovery of novel tetrahydroisoquinoline derivatives as potent and selective factor Xa inhibitors
483
Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation and structure–activity relationships. Part 2 Original Research Article
484
Discovery of novel thiourea derivatives as potent and selective β3-adrenergic receptor agonists Original Research Article
485
Discovery of novel trans-3,5-disubstituted pyrrolidinylthio-1β-methylcarbapenems Original Research Article
486
Discovery of Novel Transcriptional and Epigenetic Targets in APL by Global ChIP Analyses: Emerging Opportunity and Challenge
487
Discovery of novel α-glucosidase inhibitors based on the virtual screening with the homology-modeled protein structure Original Research Article
488
Discovery of novel, non-acidic 1,5-biaryl pyrrole EP1 receptor antagonists
489
Discovery of novel, orally active dual NK1/NK2 antagonists
490
Discovery of novel, potent and bioavailable proline-urea based macrocyclic HCV NS3/4A protease inhibitors
491
Discovery of novel, potent, and orally active spiro-urea human glucagon receptor antagonists
492
Discovery of N-phenyl nicotinamides as potent inhibitors of Kdr
493
Discovery of N-propylurea 3-benzylpiperidines as selective CC chemokine receptor-3 (CCR3) antagonists
494
Discovery of Nuclear DNA-like RNA (dRNA, hnRNA) and Ribonucleoproteins Particles Containing hnRNA
495
Discovery of Opisthorchis viverrini metacercariae in freshwater fish in southern Cambodia
496
Discovery of orally active butyrolactam 11β-HSD1 inhibitors
497
Discovery of orally active prostaglandin D2 receptor antagonists
498
Discovery of orally active pyrrolopyridine- and aminopyridine-based Met kinase inhibitors
499
Discovery of orally available spirodiketopiperazine-based CCR5 antagonists Original Research Article
500
Discovery of orally bioavailable and novel urea agonists of the high affinity niacin receptor GPR109A
501
Discovery of orally bioavailable NK1 receptor antagonists
502
Discovery of osteoblast-associated genes using cDNA microarrays
503
Discovery of OT4003, a novel, potent, and orally active cys-LT1 receptor antagonist Original Research Article
504
Discovery of Oxysterol-Derived Pharmacological Chaperones for NPC1: Implication for the Existence of Second Sterol-Binding Site Original Research Article
505
Discovery of palladium, antimony, tellurium, iodine, and xenon isotopes
506
Discovery of para-alkylthiophenoxyacetic acids as a novel series of potent and selective PPARδ agonists
507
Discovery of Peptoid Ligands for Anti-Aquaporin 4 Antibodies Original Research Article
508
Discovery of Permian sporopollen from Daftar, Taxkorgan, Xinjiang and their geological implications
509
Discovery of phenyl alanine derived ketoamides carrying benzoyl residues as novel calpain inhibitors
510
Discovery of Picomolar Slow Tight-Binding Inhibitors of α-Fucosidase
511
Discovery of Picomolar Slow Tight-Binding Inhibitors of α-Fucosidase Original Research Article
512
Discovery of pinoresinol reductase genes in sphingomonads
513
Discovery of piperazinylimidazo[1,2-a]pyridines as novel S4 binding elements for orally active Factor Xa inhibitors Original Research Article
514
Discovery of piperidine carboxamide TRPV1 antagonists
515
Discovery of piperidine-aryl urea-based stearoyl-CoA desaturase 1 inhibitors
516
Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries Original Research Article
517
Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries Original Research Article
518
Discovery of potent and cell-active allosteric dual Akt 1 and 2 inhibitors
519
Discovery of potent and orally active MTP inhibitors as potential anti-obesity agents
520
Discovery of potent and orally active tricyclic-based FBPase inhibitors Original Research Article
521
Discovery of potent and orally bioavailable heterocycle-based β3-adrenergic receptor agonists, potential therapeutics for the treatment of obesity
522
Discovery of potent and orally bioavailable N,N′-diarylurea antagonists for the CXCR2 chemokine receptor
523
Discovery of Potent and Reversible Monoacylglycerol Lipase Inhibitors Original Research Article
524
Discovery of Potent and Selective Covalent Inhibitors of JNK Original Research Article
525
Discovery of potent and selective inhibitors of 11β-HSD1 for the treatment of metabolic syndrome
526
Discovery of potent and selective orally bioavailable β-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors
527
Discovery of potent and selective PARP-1 and PARP-2 inhibitors: SBDD analysis via a combination of X-ray structural study and homology modeling Original Research Article
528
Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors
529
Discovery of potent and selective phenylalanine derived CCR3 antagonists. Part 1
530
Discovery of potent and selective phenylalanine derived CCR3 receptor antagonists. Part 2
531
Discovery of potent and selective PKC-θ inhibitors
532
Discovery of potent and selective small molecule NPY Y5 receptor antagonists
533
Discovery of potent and selective succinyl hydroxamate inhibitors of matrix metalloprotease-3 (Stromelysin-1)
534
Discovery of potent and selective β-homophenylalanine based dipeptidyl peptidase IV inhibitors
535
Discovery of potent and stable conformationally constrained analogues of the MCH R1 antagonist SB-568849
536
Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain
537
Discovery of potent BACE-1 inhibitors containing a new hydroxyethylene (HE) Scaffold: Exploration of P1′ alkoxy residues and an aminoethylene (AE) central core Original Research Article
538
Discovery of potent cholecystokinin-2 receptor antagonists: Elucidation of key pharmacophore elements by X-ray crystallographic and NMR conformational analysis Original Research Article
539
Discovery of potent CRTh2 (DP2) receptor antagonists
540
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain Original Research Article
541
Discovery of potent HIV-1 protease inhibitors incorporating sulfoximine functionality
542
Discovery of potent imidazole and cyanophenyl containing farnesyltransferase inhibitors with improved oral bioavailability
543
Discovery of potent inhibitors of pseudomonal quorum sensing via pharmacophore modeling and in silico screening
544
Discovery of potent LPA2 (EDG4) antagonists as potential anticancer agents
545
Discovery of potent pyrrolidone-based HIV-1 protease inhibitors with enhanced drug-like properties
546
Discovery of potent sulfonamide P4-capped ketoamide second generation inhibitors of hepatitis C virus NS3 serine protease with favorable pharmacokinetic profiles in preclinical species Original Research Article
547
Discovery of potent thiosemicarbazone inhibitors of rhodesain and cruzain
548
Discovery of potent T-type calcium channel blocker
549
Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties
550
Discovery of potent, orally active benzimidazole glucagon receptor antagonists
551
Discovery of potent, selective 4-fluoroproline-based thrombin inhibitors with improved metabolic stability Original Research Article
552
Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis
553
Discovery of potent, selective, and orally bioavailable oxadiazole-based dipeptidyl peptidase IV inhibitors
554
Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors
555
Discovery of Potential Natural Dipeptidyl Peptidase-4 Inhibitors for Type-2 Diabetes Treatment via Structure-Based Virtual Screening
556
Discovery of predictive rule sets for chlorophyll-a dynamics in the Nakdong River (Korea) by means of the hybrid evolutionary algorithm HEA
557
Discovery of probable Tunguska cosmic body material: anomalies of platinum group elements and rare-earth elements in peat near the Explosion Site (1908)
558
Discovery of Prognostic Signature Genes for Overall Survival Prediction in Gastric Cancer
559
Discovery of protein–protein binding disruptors using multi-component condensations small molecules
560
Discovery of proteins related to coronary artery disease using industrial-scale proteomics analysis of pooled plasma
561
Discovery of Pseudofrenelopsis from the Lower Cretaceous of Liupanshan Basin and its paleoclimatic significance
562
Discovery of pyrazine carboxamide CB1 antagonists: The introduction of a hydroxyl group improves the pharmaceutical properties and in vivo efficacy of the series
563
Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A
564
Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor Original Research Article
565
Discovery of pyrimidine benzimidazoles as Lck inhibitors: Part I
566
Discovery of pyrrole-based hepatoselective ligands as potent inhibitors of HMG-CoA reductase Original Research Article
567
Discovery of quinazolines as a novel structural class of potent inhibitors of NF-κB activation Original Research Article
568
Discovery of radiolaria and conodonts in the Carboniferous–Permian of San Salvador Patlanoaya (Puebla, Mexico); biostratigraphic implications
569
Discovery of radiolaria from Upper Cretaceous Oceanic Red Beds in Daba, Kangmar and its paleogeographic implication
570
Discovery of recurrent multiple brain states in non-convulsive status epilepticus
571
Discovery of Ro 48-5695: A potent mixed endothelin receptor antagonist optimized from bosentan
572
Discovery of rubidium, strontium, molybdenum, and rhodium isotopes
573
Discovery of safety biomarkers for atorvastatin in rat urine using mass spectrometry based metabolomics combined with global and targeted approach Original Research Article
574
Discovery of samarium, europium, gadolinium, and terbium isotopes
575
Discovery of sapphirine-bearing Mg–Al granulites in the North China Craton: Implications for Paleoproterozoic ultrahigh temperature metamorphism
576
Discovery of SB-705498: A potent, selective and orally bioavailable TRPV1 antagonist suitable for clinical development
577
Discovery of scandium, titanium, mercury, and einsteinium isotopes
578
Discovery of selective aldo-keto reductase ligands—an on-bead assay strategy
579
Discovery of selective and nonpeptidic cathepsin S inhibitors
580
Discovery of selective dopamine D3 ligands: I. Dimeric 2-[4-(3-aminopropoxy)phenyl]benzimidazole antagonists
581
Discovery of selective dopamine D3 ligands: II. 2-[4-[3-(4-aryl-1-piperazinyl)propoxy]phenyl]benzimidazole partial agonists
582
Discovery of selective dopamine D4 receptor antagonists: 1-Aryloxy-3-(4-aryloxypiperidinyl)-2-propanols
583
Discovery of selective hydroxamic acid inhibitors of tumor necrosis factor-α converting enzyme
584
Discovery of selective imidazole-based inhibitors of mammalian 15-lipoxygenase: Highly potent against human enzyme within a cellular environment
585
Discovery of selective metal-binding peptoids using 19F encoded combinatorial libraries
586
Discovery of selective phosphonamide-based inhibitors of tumor necrosis factor-α converting enzyme (TACE)
587
Discovery of selective, small-molecule inhibitors of RNA complexes—1. The tat protein/TAR RNA complexes required for HIV-1 transcription Original Research Article
588
Discovery of selective, small-molecule inhibitors of RNA complexes—II. Self-splicing group I intron ribozyme Original Research Article
589
Discovery of small molecule agonists for the bombesin receptor subtype 3 (BRS-3) based on an omeprazole lead
590
Discovery of small molecule antagonists of TRPV1
591
Discovery of small molecule benzimidazole antagonists of the chemokine receptor CXCR3
592
Discovery of small molecule inhibitors of integrin αvβ3 through structure-based virtual screening
593
Discovery of small-molecule inhibitors of tyrosinase
594
Discovery of soluble epoxide hydrolase inhibitors from natural products
595
Discovery of Specific Inhibitors of Human USP7/HAUSP Deubiquitinating Enzyme Original Research Article
596
Discovery of substituted 3,4-Diphenyl-thiazoles as a novel class of monoamine transporter inhibitors through 3-D pharmacophore search using a new pharmacophore model derived from mazindol
597
Discovery of substituted 8,9-dicarboxyldibenzo [2,3:5,6] bicyclo [5.2.0] nonan-4-ones with moderate binding affinity to the endothelin ETA and ETB receptors
598
Discovery of subtle effects in a human intervention trial through multilevel modeling
599
Discovery of subtype-selective NMDA receptor ligands: 4-Benzyl-1-piperidinylalkynylpyrroles, pyrazoles and imidazoles as NR1 /2B antagonists
600
Discovery of sulfonylalkylamides: A new class of orally active factor Xa inhibitors Original Research Article
601
Discovery of superoxide reductase: an historical perspective
602
Discovery of symmetry by voting method
603
Discovery of tantalum, rhenium, osmium, and iridium isotopes
604
Discovery of tertiary aminoacids as dual PPARα/γ agonists-I
605
Discovery of tetrahydro-β-carbolines as inhibitors of the mitotic kinesin KSP Original Research Article
606
Discovery of tetralin ureas as potent melanin concentrating hormone 1 receptor antagonists
607
Discovery of the arsenic isotopes
608
Discovery of the astatine, radon, francium, and radium isotopes
609
Discovery of the barium isotopes
610
Discovery of the bi-layered structure in spin-coated polyacrylamide films on the gold surface
611
Discovery of the cadmium isotopes
612
Discovery of the calcium, indium, tin, and platinum isotopes
613
Discovery of the catechol structural moiety as a Stat3 SH2 domain inhibitor by virtual screening
614
Discovery of the cerium isotopes
615
Discovery of the cobalt isotopes
616
Discovery of the connection among age-related macular degeneration, MTHFR C677T and PAI 1 4G/5G gene polymorphisms, and body mass index by means of Bayesian inference methods
617
Discovery of the content of rumination thoughts among women with marital conflicts: Qualitative study
618
Discovery of the cross-coupling reaction between Grignard reagents and C(sp2) halides catalyzed by nickel–phosphine complexes
619
Discovery of the Endocannabinoid System: A Breakthrough in Neuroscience
620
Discovery of the Eucalyptus canker pathogen Chrysoporthe cubensis on native Miconia (Melastomataceae) in Colombia
621
Discovery of the first antibacterial small molecule inhibitors of MurB
622
Discovery of the first non-planar flavonoid that can strongly inhibit xanthine oxidase: protoapigenone 1′-O-propargyl ether
623
Discovery of the first Quaternary maar in the Bohemian Massif, Central Europe, based on combined geophysical and geological surveys
624
Discovery of the first series of inhibitors of human papillomavirus type 11: inhibition of the assembly of the E1–E2–Origin DNA complex
625
Discovery of the genera Bolothrips Priesner, 1926 and Cephalothrips Uzel, 1895 (Thysanoptera: Phlaeothripidae) from the Oriental region
626
Discovery of the genus Cinetus Jurine, 1807 (Hymenoptera: Diapriidae) from Iran, with five species records
627
Discovery of the gold isotopes
628
Discovery of the hypothalamic gonadotropin-releasing hormone pulse generator and of its physiologic significance
629
Discovery of the iron isotopes
630
Discovery of the Isotopes with 11≤Z≤19
631
Discovery of the krypton isotopes
632
Discovery of the largest impact crater field on Earth in the Gilf Kebir region, Egypt
633
Discovery of the Life-Organizing Principle: In Search of the Fundamentals Laws of Life, E.M. Elsheik. iUniverse LLC, Bloomington, USA (2014)
634
Discovery of the Life-Organizing Principle: In Search of the Fundamentals Laws of Life, E.M. Elsheik. iUniverse LLC, Bloomington, USA (2014)
635
Discovery of the Low-Redshift Optical Afterglow of GRB 011121 and Its Progenitor Supernova SN 2001ke
636
Discovery of the male of the subterranean species niphargus ozimeci karaman, g., 2011 (fam. niphargidae) in bosnia Herzegovina (contribution to the knowledge of the amphipoda 262)
637
Discovery of the male of the subterranean species niphargus ozimeci karaman, g., 2011 (fam. niphargidae) in bosnia & Herzegovina (contribution to the knowledge of the amphipoda 262)
638
Discovery of the most rapidly-rotating, non-degenerate, magnetic massive star by the MiMeS collaboration
639
Discovery of the new proton emitter 144Tm
640
Discovery of the New Target for Identification of Mycobacterium tuberculosis
641
Discovery of the Ordovician Millbrig K-bentonite Bed in the Trenton Group of New York State: implications for regional correlation and sequence stratigraphy in eastern North America
642
Discovery of the Oriental genus Piyumoides Leclercq, 1963 (Hymenoptera, Crabronidae) in the Indian subcontinent with the description of a new species
643
Discovery of the Paleo-Tethys residual peridotites along the Anyemaqen–KunLun suture zone (North Tibet)
644
Discovery of the predatory mite Neoseiulus californicus (Acari: Phytoseiidae) in some rose greenhouses in Iran and describing variation in spermathecal calyx shape
645
Discovery of the rotational spectrum of the weakly bound complex CO–H2
646
Discovery of the silver isotopes
647
Discovery of the thallium, lead, bismuth, and polonium isotopes
648
Discovery of the tungsten carbonyl-catalyzed endo-selective alkynyl alcohol cycloisomerization reaction: applications to stereoselective syntheses of d-olivose, d-olivose disaccharide substructures of landomycin and mithramycin
649
Discovery of the tungsten isotopes
650
Discovery of the vanadium isotopes
651
Discovery of the Yamato Meteorites in 1969
652
Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: Design, synthesis and structure–activity relationship studies
653
Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 2: Metabolism-directed optimization studies towards orally bioavailable derivatives
654
Discovery of thieno[2,3-c]pyridines as potent COT inhibitors
655
Discovery of thienopyridines as Src-family selective Lck inhibitors
656
Discovery of Thioazepinone Ligands for Src SH2: From Non-specific to Specific Binding
657
Discovery of thiochroman and chroman derivatives as pure antiestrogens and their structure–activity relationship Original Research Article
658
Discovery of thiochroman derivatives bearing a carboxy-containing side chain as orally active pure antiestrogens
659
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides
660
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: Tertiary amides
661
Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: Tertiary amides
662
Discovery of three new mordellids (Coleoptera, Tenebrionoidea) from the Yixian Formation of western Liaoning, China
663
Discovery of TNF Inhibitors from a DNA-Encoded Chemical Library based on Diels-Alder Cycloaddition Original Research Article
664
Discovery of trans-3,4′-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation
665
Discovery of trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H),1′-cyclohexane]-4′-carboxamide, a potent and orally active neuropeptide Y Y5 receptor antagonist Original Research Article
666
Discovery of triazolinone non-nucleoside inhibitors of HIV reverse transcriptase
667
Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatB
668
Discovery of two northern hemisphere Armillaria species on Proteaceae in South Africa
669
Discovery of two ophiolite complexes of different ages in the Khoy area (NW Iran)
670
Discovery of two potential DAZL gene markers for sperm quality in boars by population association studies
671
DISCOVERY OF ULTRACOMPACT DWARF GALAXIES IN THE VIRGO CLUSTER
672
Discovery of underground argon with low level of radioactive 39Ar and possible applications to WIMP dark matter detectors
673
Discovery of underground argon with low level of radioactive 39Ar and possible applications to WIMP dark matter detectors
674
Discovery of Unertan Syndrome and Reverse Evolution: As An “Aha!” Experience
675
Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans
676
Discovery of Wall Teichoic Acid Inhibitors as Potential Anti-MRSA β-Lactam Combination Agents Original Research Article
677
Discovery of whitlockite in mantle xenoliths: Inferences for water- and halogen-poor fluids and trace element residence in the terrestrial upper mantle
678
Discovery of Widespread GTP-Binding Motifs in Genomic DNA and RNA Original Research Article
679
Discovery of X-Ray Burst Oscillations from a Neutron Star X-Ray Transient in the Globular Cluster NGC 6440
680
Discovery of X-Ray Quasi-Periodic Oscillations from an Ultraluminous X-Ray Source in M82: Evidence against Beaming
681
Discovery of yttrium, zirconium, niobium, technetium, and ruthenium isotopes
682
Discovery of zinc, selenium, bromine, and neodymium isotopes
683
Discovery of zoniporide: A potent and selective sodium–hydrogen exchanger type 1 (NHE-1) inhibitor with high aqueous solubility
684
Discovery of β-benzamido hydroxamic acids as potent, selective, and orally bioavailable TACE inhibitors
685
Discovery of γ-secretase inhibitors efficacious in a transgenic animal model of Alzheimer’s disease
686
Discovery potential for doubly charged Higgs bosons in e+e− collisions at LEP
687
Discovery potential for new physics in view of the RHIC-Spin upgrade
688
Discovery potential of new boson image in the Minimal Higgsless model at LHC Original Research Article
689
Discovery prospects for a supernova signature of biogenic origin
690
Discovery stage pharmacokinetics using dried blood spots
691
Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay Original Research Article
692
Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator
693
Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk)
694
Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors
695
Discovery, SAR, synthesis, pharmacokinetic and biochemical characterization of A-192411: A novel fungicidal lipopeptide-(I)
696
Discovery, structure and biological activities of cyclotides
697
Discovery, structure and HIV-1 integrase inhibitory activities of integracins, novel dimeric alkyl aromatics from Cytonaema sp.
698
Discovery, structure–activity relationship study, and oral analgesic efficacy of cyproheptadine derivatives possessing N-type calcium channel inhibitory activity Original Research Article
699
Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1) Original Research Article
700
Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2) Original Research Article
701
Discovery, synthesis and biological evaluation of novel glucokinase activators
702
Discovery, synthesis, and structure–activity studies of tetrazole based growth hormone secretagogues
703
Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure–activity relationships of 2-methoxystypandrone and its analogues
704
Discovery, visualization and performance analysis of enterprise workflow
705
Discrepancies among clinical, histological and immunological findings in IgA pemphigus: a case report and literature survey
706
Discrepancies Between Biopsy Gleason Score and Radical Prostatectomy Specimen Gleason Score: An Iranian Experience
707
Discrepancies between catheter and Doppler estimates of valve effective orifice area can be predicted from the pressure recovery phenomenon: practical implications with regard to quantification of aortic stenosis severity
708
Discrepancies between classic anatomy and modern gynecologic surgery on pelvic connective tissue structure: Harmonization of those concepts by collaborative cadaver dissection
709
Discrepancies between desired and perceived measures of performance of IS professionals: Views of the IS professionals themselves and the users
710
Discrepancies between desired and perceived measures of performance of IS professionals: Views of the IS professionals themselves and the users
711
Discrepancies between echocardiographic measurements of left ventricular mass in a healthy adult population
712
Discrepancies between ecological and individual data on fruit and vegetable consumption in fifteen countries
713
Discrepancies between ergosterol and the phospholipid fatty acid 18:2ω6,9 as biomarkers for fungi in boreal forest soils
714
Discrepancies between ergosterol and the phospholipid fatty acid 18:2ω6,9 as biomarkers for fungi in boreal forest soils
715
Discrepancies Between Free Vibration of FML and Composite Cylindrical Shells Reinforced by CNTs
716
Discrepancies between metric dimension and partition dimension of a connected graph Original Research Article
717
Discrepancies between microscopic (TEM) and macroscopic (texture) observations in high temperature deformation of FeAl and Fe3Al-based alloys
718
Discrepancies between microscopic (TEM) and macroscopic (texture) observations in high temperature deformation of FeAl and Fe3Al-based alloys
719
Discrepancies between N-Acetyl Cysteine Prescription based on Patient’s History and Plasma Acetaminophen Level
720
Discrepancies Between Normative and Descriptive Models of Decision Making and the Understanding/Acceptance Principle,
721
Discrepancies between roughness measurements obtained with phase-shifting and white-light interferometry
722
Discrepancies between Self- and Clinical Staff Members’ Perception of Cognitive Functioning among Patients with Schizophrenia Undergoing Long-Term Hospitalization
723
Discrepancies between self and observer ratings of depression: The relationship to demographic, clinical and personality variables
724
Discrepancies between self-report and objective measures for stimulant drug use in HIV: Cognitive, medication adherence and psychological correlates
725
Discrepancies between self-reported and observed physical function in the elderly: the influence of response shift and other factors
726
Discrepancies between self-reported years of education and estimated reading level among elderly community-dwelling African-Americans: Analysis of the MOAANS data
727
Discrepancies Between Sizer and Valve Dimensions: Implications for Small Aortic Root
728
Discrepancies between the Speech of Male and Female in Lecturing: Language Management in Focus
729
Discrepancies in brine density databases at geothermal conditions
730
Discrepancies in Cancer Mortality Estimates
731
Discrepancies in diagnosing Osteopenia and Osteoporosis with bone densitometry at spine and femoral neck
732
Discrepancies in earthquake location between ISC and other agencies
733
Discrepancies in Evaluating Farm Management Routines as Risk Factors of Raw Milk and Udder Hygiene in Selected Dairy Farms of Fars Province, Iran
734
Discrepancies in initial death certificate diagnoses in sudden unexpected out-of-hospital deaths: the role of cardiovascular autopsy
735
Discrepancies in interpretation of ED body computed tomographic scans by radiology residents
736
Discrepancies in interpretation of night-time emergency computed tomography scans by radiology residents
737
Discrepancies in mental functioning relative to word knowledge on the Speed and Capacity of Language-Processing Test
738
Discrepancies in military middle-school adolescentsʹ and parentsʹ perceptions of family functioning, social support, anger frequency, and concerns
739
Discrepancies in pelvic anatomy
740
Discrepancies in performance status scores as determined by cancer patients and oncologists: are they influenced by depression?
741
Discrepancies in SART (Society for Assisted Reproductive Technology) reporting
742
Discrepancies in the Monte Carlo simulations of propagation of ultra-high energy cosmic-ray photons in the geomagnetic field
743
Discrepancies in the morphology and physical properties of amorphous and crystalline sprayed lanthanum nickel oxide films Original Research Article
744
Discrepancy and signed domination in graphs and hypergraphs
745
Discrepancy behaviour in the non-asymptotic regime Original Research Article
746
Discrepancy between actual and ideal body images: Impact on eating and exercise behaviors
747
Discrepancy between Actual and Theoretical Anterior Chamber Depth in Patients with Morcher Posterior Chamber Intraocular Lens
748
Discrepancy between Admission and Discharge Diagnoses in Central Serbia: Analysis by the Groups of International Classification of Diseases, 10th Revision
749
Discrepancy Between Admission Diagnosis and Discharge Diagnosis in Cardiovascular Diseases: An Analysis Based On the Groups of International Classification Disease, 10th Revision
750
Discrepancy between auditory brainstem responses, auditory steady-state responses, and auditory behavior in two patients with Pelizaeus-Merzbacher disease
751
Discrepancy between clinical staging through bimanual palpation and pathological staging after cystectomy
752
Discrepancy between fatigue and dwell-fatigue behavior of near alpha titanium alloys simulated by cellular automata
753
Discrepancy Between Intraoperative Transesophageal Echocardiography and Postoperative Transthoracic Echocardiography in Assessing Congenital Valve Surgery
754
Discrepancy between photoluminescence and photoresponse intensities in n-InAs/GaAs and InAs/n-GaAs quantum-dot heterostructures
755
Discrepancy between second and first opinion in surgical oncological patients
756
Discrepancy between serum leptin values and total body fat in response to the oral growth hormone secretagogue MK-677
757
Discrepancy between Sr isotope and biostratigraphic datings of the upper middle and upper Miocene successions (Eastern North Sea Basin, Denmark)
758
Discrepancy between subjective and objective ratings for negative symptoms
759
Discrepancy between the theory and polarization observations in the 530.3 nm solar coronal line Original Research Article
760
Discrepancy between theory and real computation on the stability of some finite element schemes
761
Discrepancy detection and developmental changes in attentional engagement in infancy
762
Discrepancy estimates based on Haar functions Original Research Article
763
Discrepancy for uniform design of experiments with mixtures
764
Discrepancy in ABO Blood Grouping in a Blood Donor: A Case Report
765
Discrepancy in different numbers of colors Original Research Article
766
Discrepancy in generalized arithmetic progressions
767
Discrepancy in pd breakup reaction at image Original Research Article
768
Discrepancy in regression estimates between log-normal and gamma: some case studies
769
Discrepancy in Screening Performances of Different Rapid Test Kits for SARS-CoV-2; a Letter to Editor
770
Discrepancy in serum carcinoembryonic antigen levels by measuring kits
771
Discrepancy in serum carcinoembryonic antigen levels by measuring kits: Reply
772
Discrepancy in the preferences of place of death between terminally ill cancer patients and their primary family caregivers in Taiwan
773
Discrepancy measures for selecting optimal combination of parameter values in object-based image analysis
774
Discrepancy of (centered) arithmetic progressions in
775
Discrepancy of Arithmetic Progressions in Higher Dimensions Original Research Article
776
Discrepancy of Centered Arithmetic Progressions in (Extended Abstract)
777
Discrepancy of computed tomographic image between lung and mediastinal windows as a prognostic implication in small lung adenocarcinoma
778
Discrepancy of Graham Greene
779
Discrepancy of response of hPTH administration and its withdrawal between trabecular and cortical bone sites in ovx rats
780
Discrepancy of structural stability against temperature between metallic liquids and their glasses
781
Discrepancy of Sums of Arithmetic Progressions
782
Discrepancy of Sums of two Arithmetic Progressions
783
Discrepancy of the spectral data between adunctin E and the synthetic one
784
Discrepancy of Weyl Sequences (nα) Perturbed by Rationally Periodic Functions
785
Discrepancy principle for DSM II
786
Discrepancy principle for the dynamical systems method
787
Discrepancy rates of preliminary and final reports for after-hours pediatric teleradiology interpretations
788
Discrepancy searchfortheflexiblejobshopschedulingproblem
789
Discrepancy with respect to convex polygons
790
Discrepancy-based error estimates for Quasi-Monte Carlo I. General formalism Original Research Article
791
Discrepancy-based error estimates for Quasi-Monte Carlo II. Results in one dimension Original Research Article
792
Discrepancy-based error estimates for Quasi-Monte Carlo III. Error distributions and central limits Original Research Article
793
Discrepant analysis and screening for Chlamydia trachomatis
794
Discrepant analysis and screening for Chlamydia trachomatis
795
Discrepant analysis and screening for Chlamydia trachomatis
796
Discrepant analysis and screening for Chlamydia trachomatis
797
Discrepant analysis and screening for Chlamydia trachomatis
798
Discrepant analysis and screening for Chlamydia trachomatis
799
Discrepant analysis—or behaviour?
800
Discrepant and congruent high self-esteem: Behavioral self-handicapping as a preemptive defensive strategy
801
Discrepant Cytogenetic and Fluorescence In Situ Hybridization Results in a 26-Year-Old Male with Early T-Cell Acute Lymphocytic Leukemia
802
Discrepant epidemiological patterns between classical and atypical scrapie in sheep flocks under French TSE control measures
803
Discrepant fluency increases subjective truth
804
Discrepant illness perceptions, affect and expressed emotion in people with psychosis and their carers
805
Discrepant impacts of land use and land cover on urban heat islands: A case study of Shanghai, China
806
Discrepin, a new peptide of the sub-family α-ktx15, isolated from the scorpion Tityus discrepans irreversibly blocks K+-channels (IA currents) of cerebellum granular cells
807
Discrete (carbon free) chelate rings derived from sodium tetraphenylimidodiphosphinochalcogenides (S and Se) and 15-crown-5
808
Discrete 3D model as complimentary numerical testing for anisotropic damage
809
Discrete abstractions for robot motion planning and control in polygonal environments
810
Discrete accidental symmetry for a particle in a constant magnetic field on a torus Original Research Article
811
Discrete acoustic emission waves during stick–slip friction between steel samples
812
Discrete actions on nilpotent Lie groups and negatively curved spaces
813
Discrete active models and applications
814
Discrete Adaptive Sliding Mode Control of a State-Space System with a Bounded Disturbance
815
Discrete adaptive sliding-mode control of a class of stochastic systems
816
Discrete adaptive sliding-mode tracking controller
817
Discrete ADM: A tool for solving a class of classic and fractional difference problems
818
Discrete Adomian Decomposition solution of Nonlinear Fredholm Integral Equation
819
Discrete algebraic estimator design for non-linear Liouvillian systems with sampled output: Application to a class of stirred bioreactor
820
Discrete analog electronics for high-resistivity silicon detectors used for X-ray and γ-ray spectroscopy in whole-body monitoring
821
Discrete analog electronics for high-resistivity silicon detectors used for X-ray and γ-ray spectroscopy in whole-body monitoring
822
Discrete analogue of Fučik spectrum of the Laplacian
823
Discrete anchoring: Bulk-substrate coupling in lattice models
824
Discrete and 1D coordination polymeric chloro-bridged copper(II) dimers exhibiting ferro- and antiferromagnetic exchange coupling: Magneto-structural correlations and non-covalent interactions
825
Discrete and continuous conceptualizations of science: Implications for knowledge domain visualization
826
Discrete and continuous deformation during nanoindentation of thin films Original Research Article
827
Discrete and continuous dynamical systems
828
Discrete and continuous expectation formulae for level-crossings, upcrossings and excursions of ellipsoidal processes
829
Discrete and continuous joint coupling relationships in uninjured recreational runners
830
Discrete and continuous linearizable equations
831
Discrete and Continuous Mathematical Models of DNA Branch Migration
832
Discrete and continuous maximum principles for parabolic and elliptic operators
833
Discrete and continuous models for in plane loaded random elastic brickwork
834
Discrete and continuous models of the dynamics of pelagic fish: Application to the capelin Original Research Article
835
Discrete and continuous nonlinear models for the vibrating rod
836
Discrete and continuous reproductive tactics in a hermaphroditic society
837
Discrete and continuous state population models in a noisy world
838
Discrete and continuous time cointegration
839
Discrete and continuous time simulations of spatial ecological processes predict different final population sizes and interspecific competition outcomes
840
Discrete and continuous time simulations of spatial ecological processes predict different final population sizes and interspecific competition outcomes
841
Discrete- and continuous-time local cosine bases with multiple overlapping
842
Discrete and continuum modelling of excavator bucket filling
843
Discrete and cyclical movements: unified dynamics or separate control?
844
Discrete and dynamic versus continuous and static loading policy for a multi-compartment vehicle
845
Discrete and infinite metal–organometallic coordination networks consisting of europium(III) nodes and quinone π-complexes as spacers
846
Discrete and oscillatory matrix models in Chern–Simons theory Original Research Article
847
Discrete anomalies and the null cone of SYM theories
848
Discrete anomaly matching Original Research Article
849
Discrete approach for flow field designs of parallel channel configurations in fuel cells
850
Discrete Approach to PWL Analog Modeling in VHDL Environment
851
Discrete approach to study fracture energy absorption under dynamic loading
852
Discrete approximation by variational vector splines for noisy data Original Research Article
853
Discrete Approximation of Unbounded Operators and Approximation of their Spectra Original Research Article
854
Discrete approximation to the global spectrum of the tangent operator for flow past a circular cylinder Original Research Article
855
Discrete approximationheuristicsforthecapacitatedcontinuouslocation–allocation problemwithprobabilisticcustomerlocations
856
Discrete approximations of solutions and derivatives for a singularly perturbed parabolic convection–diffusion equation
857
Discrete approximations of the Föppl–Von Kármán shell model: From coarse to more refined models
858
Discrete Approximations to Continuum Optimal Flow Problems
859
Discrete approximations to optimization of neutral functional differential inclusions
860
Discrete approximations to real-valued leaf sequencing problems in radiation therapy Original Research Article
861
Discrete approximations, relaxation, and optimization of one-sided Lipschitzian differential inclusions in Hilbert spaces
862
Discrete artificial boundary conditions for nonlinear Schrِdinger equations
863
Discrete artificial boundary conditions for transient scalar wave propagation in a 2D unbounded layered media Original Research Article
864
Discrete bands of petroleum hydrocarbons and molecular organic markers identified within massive coral skeletons
865
Discrete bandwidth allocation considering fairness and transmission load in multicast networks
866
Discrete bandwidth visual feedback increases structure of output as compared to continuous visual feedback in isometric force control tasks
867
Discrete Bargmann and Neumann systems and finite-dimensional integrable systems
868
Discrete behavior of Seshadri constants on surfaces
869
Discrete bilevel programming: Application to a natural gas cash-out problem
870
Discrete bilinear stochastic systems with time-varying delay: Stability analysis and control synthesis
871
Discrete biorthogonal wavelet transforms as block circulant matrices Original Research Article
872
Discrete bipolar universal integrals
873
Discrete bond-weighted random scission of linear polymers
874
Discrete boundary conditions for elasticity problems with singularities Original Research Article
875
Discrete boundary conditions for problems with interface Original Research Article
876
Discrete branching processes, QCD and multiparticle distributions
877
Discrete breathers — Advances in theory and applications
878
Discrete breathers — Advances in theory and applications
879
Discrete breathers and nonlinear normal modes in monoatomic chains
880
Discrete breathers in aperiodic diatomic FPU lattices with long range order
881
Discrete breathers in Josephson ladders
882
Discrete breathers in nonlinear Schrِdinger hypercubic lattices with arbitrary power nonlinearity
883
Discrete breathers in thermal equilibrium: distributions and energy gaps
884
Discrete breathers in transient processes and thermal equilibrium
885
Discrete breathers in two-dimensional anisotropic nonlinear Schrِdinger lattices
886
Discrete breathers in two-dimensional nonlinear lattices
887
Discrete breathers: classical and quantum
888
Discrete Breathers: Localization and transfer of energy in discrete Hamiltonian nonlinear systems
889
Discrete buckling model for corrugated beam
890
Discrete calculus methods for diffusion
891
Discrete Calderon’s projections on parallelepipeds and their application to computing exterior magnetic fields for FRC plasmas
892
Discrete camera calibration from pixel streams
893
Discrete capacity and flow assignment algorithms with performance guarantee
894
Discrete cellular entry points discovered in neuronal membrane
895
Discrete chaos induced by heteroclinic cycles connecting repellers in Banach spaces Original Research Article
896
Discrete characterization of cohesion in gas–solid flows
897
Discrete characterization tools for cohesive granular material
898
Discrete charge dielectric model of electrostatic energy
899
Discrete chirp-Fourier transform and its application to chirp rate estimation
900
Discrete choice modeling with nonstationary panels applied to exchange rate regime choice
901
Discrete choice models and optimal two-part tariffs in the presence of externalities: optimal taxation of cars
902
Discrete choice models of pedestrian walking behavior
903
Discrete choice models with capacity constraints: An empirical analysis of the housing market of the greater Paris region
904
Discrete choice models with latent choice sets
905
DISCRETE CHOICE MODELS WITH MULTIPLE UNOBSERVED CHOICE CHARACTERISTICS∗
906
Discrete choice survey experiments: A comparison using flexible methods
907
Discrete Choice under Preference Uncertainty: An Improved Structural Model for Contingent Valuation
908
Discrete choice with an oddball alternative
909
Discrete Choquet integral and some of its symmetric extensions
910
Discrete clay diagenesis in a very low-permeable sequence constrained by an isotopic (K-Ar and Rb-Sr) study
911
Discrete cloud activity in Saturn’s equator during 1995, 1996 and 1997
912
Discrete Clutch Sizes, Local Mate Competition, and the Evolution of Precise Sex Allocation
913
Discrete Cocompact Subgroups of the Four-Dimensional Nilpotent Connected Lie Group and Their Group C∗-Algebras1
914
Discrete cohesive zone model for mixed-mode fracture using finite element analysis
915
Discrete collocation method for Volterra type weakly singular integral equations with logarithmic kernels
916
Discrete combinatorial geometry
917
Discrete competing risk model with application to modeling bus-motor failure data
918
Discrete competing risk model with application to modeling bus-motor failure data
919
Discrete computer simulation of bedrooms
920
Discrete Concavity and Zeros of Polynomials
921
Discrete conjugate boundary value problems Original Research Article
922
Discrete conservation and coupling strategies in nonlinear aeroelasticity Original Research Article
923
Discrete conservation laws and the convergence of long time simulations of the mkdv equation
924
Discrete constant-velocity-equivalent multirate models for target tracking
925
Discrete contact mechanics of a fibrillar surface with backing layer interactions
926
Discrete continuation method for boundary value problems on bounded sets in Banach spaces
927
Discrete control for a computer hard disk by using a fractional order hold device
928
Discrete control of unified power flow controller for stability improvement
929
Discrete conventional signalling of a continuous variable
930
Discrete conversion of gamma rays in 229Th and in highly ionized 125TeQ ions
931
Discrete convexity and unimodularity—I
932
Discrete Coons patches Original Research Article
933
Discrete Copulas
934
Discrete cosine transform LSQR methods for multidimensional ill-posed problems
935
Discrete Countercurrent Contacting; An Experimental Method for Developing Continuous Countercurrent Reactors
936
Discrete crack analysis of concrete gravity dams based on the known inertia force field of linear response analysis
937
Discrete crack modelling of ductile fracture driven by non-local softening plasticity
938
Discrete crack path prediction by an adaptive cohesive crack model
939
Discrete cubic water cluster: An unusual building block of 3D supramolecular network
940
Discrete Curves in and the Toda Lattice
941
Discrete damage zone model for fracture initiation and propagation
942
Discrete data assimilation in the Lorenz and 2D Navier–Stokes equations
943
Discrete deformations in Type I vacua
944
Discrete degradation modeling using generalized mixed effect model
945
Discrete Derivatives of Sequences
946
Discrete Design Optimization of Small Open Type Dry Transformers
947
Discrete deterministic and stochastic blending problems with two quality characteristics: aluminum blending
948
Discrete deterministic and stochastic blending problems with two quality characteristics: aluminum blending
949
Discrete devaluations and multiple equilibria in a first generation model of currency crises
950
Discrete devaluations and multiple equilibria in a first generation model of currency crises
951
Discrete Dichotomies and Bifurcations from Critical Homoclinic Orbits
952
Discrete Differential Geometry
953
Discrete dihedral-angle modulation in porphyrin wheels adsorbed on Cu(1 0 0) observed by scanning tunneling microscopy
954
Discrete dipole approximation simulations of scattering by particles with hierarchical structure
955
Discrete direct and adjoint sensitivity analysis for arbitrary Mach number flows
956
Discrete Dirichlet-to-Neumann maps for unbounded domains Original Research Article
957
Discrete dislocation analyses of circular nanoindentation and its size dependence in polycrystals Original Research Article
958
Discrete dislocation analysis of the wedge indentation of polycrystals Original Research Article
959
Discrete dislocation and continuum descriptions of plastic flow
960
Discrete dislocation and continuum descriptions of plastic flow
961
Discrete dislocation density modelling of single phase FCC polycrystal aggregates Original Research Article
962
Discrete dislocation dynamics analysis of the effect of lattice orientation on void growth in single crystals
963
Discrete dislocation dynamics by an O(N) algorithm
964
Discrete dislocation dynamics modelling of mechanical deformation of nickel-based single crystal superalloys
965
Discrete dislocation dynamics modelling of microvoid growth and its intrinsic mechanism in single crystals Original Research Article
966
Discrete dislocation dynamics simulation of cutting of γ′ precipitate and interfacial dislocation network in Ni-based superalloys
967
Discrete dislocation dynamics simulations of plasticity at small scales Original Research Article
968
Discrete dislocation dynamics simulations of surface induced size effects in plasticity
969
Discrete dislocation dynamics simulations to interpret plasticity size and surface effects in freestanding FCC thin films
970
Discrete dislocation dynamics study on interaction between prismatic dislocation loop and interfacial network dislocations
971
Discrete dislocation dynamics: an important recent break-through in the modelling of dislocation collective behaviour
972
Discrete dislocation modeling in three-dimensional confined volumes
973
Discrete dislocation modeling in three-dimensional confined volumes
974
Discrete dislocation modeling of fatigue crack propagation Original Research Article
975
Discrete dislocation modeling of fracture in plastically anisotropic metals
976
Discrete dislocation modelling of near threshold fatigue crack propagation
977
Discrete dislocation modelling of submicron indentation
978
Discrete dislocation plasticity analysis of single crystalline thin beam under combined cyclic tension and bending Original Research Article
979
Discrete dislocation plasticity analysis of single slip tension
980
Discrete dislocation plasticity analysis of static friction Original Research Article
981
Discrete dislocation plasticity analysis of the grain size dependence of the flow strength of polycrystals
982
Discrete dislocation plasticity analysis of the wedge indentation of films
983
Discrete dislocation plasticity modeling of short cracks in single crystals Original Research Article
984
Discrete dislocation simulation of nanoindentation
985
Discrete dislocation simulation of nanoindentation: Indentation size effect and the influence of slip band orientation Original Research Article
986
Discrete dislocation simulation of nanoindentation: the effect of moving conditions and indenter shape
987
Discrete dislocation simulation of nanoindentation: the effect of moving conditions and indenter shape
988
Discrete dislocation simulation of nanoindentation: the effect of moving conditions and indenter shape
989
Discrete dislocation simulation of nanoindentation: The effect of statistically distributed dislocations
990
Discrete dislocation simulation of plastic deformation in metal thin films Original Research Article
991
Discrete dislocation simulations of the development of a continuum plastic zone ahead of a stationary Mode III crack
992
Discrete dislocations in graphene
993
Discrete dispersion of single-walled carbon nanotubes
994
Discrete distance operator on rectangular grids
995
DISCRETE DISTRIBUTIONS CONNECTED WITH THE BIVARIATE BINOMIAL
996
Discrete distributions in the extended FGM family: The p.g.f. approach
997
Discrete distributions with maximum expected value of the maximum
998
Discrete double directors shell element for the functionally graded material shell structures analysis
999
Discrete dragline attachment induces aggregation in spiderlings of a solitary species
1000
Discrete Dubrovin equations and separation of variables for discrete systems
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